Results 331 to 340 of about 361,542 (380)

Maternal inheritance suppresses CAA and amyloid plaques in 5xFAD (Tg7031)/APOE4 mice. [PDF]

Neuron
Saadi F, Katritch IV, Parhizkar S, Lugo B, Cho Y, Ulrich JD, Holtzman DM.   +6 more
europepmc   +1 more source

Engineering single-vector logic-gated CAR T cells with transgene sizes beyond current limitations. [PDF]

J Immunother Cancer
Rommel PC, Engel NW, Malachowski JK, Shukla D, Hodson IR, Gonzales D, van der Loo JCM, Young RM, Riley JL, Levine BL, June CH.   +10 more
europepmc   +1 more source

Toxic effects of GAL80 and RNAi against fluorescent proteins on motor performance in <i>Drosophila</i>. [PDF]

MicroPubl Biol
Mizzi K, Grech F, Tabone S, Cacciottolo R, Cauchi RJ.   +4 more
europepmc   +1 more source

Refined Transgenic Mouse Models Which Recapitulate the Natural Features of Chronic Wasting Disease With Rapid Prion Disease Onsets. [PDF]

J Infect Dis
DeFranco JP, Kim S, Atkinson ZN, Crowell J, Lei S, Bian J, Telling GC.   +6 more
europepmc   +1 more source

Acute lymphoblastic B‐cell leukemia or CAR‐T cell related skin changes – a relevant diagnostic challenge

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Farzan Solimani, Amrei Dilling, Konrad Heisterkamp, Frederik Damm, Olaf Penack, Christian Oberender, Philipp Le‐Coutre, Martina Rudelius, Kamran Ghoreschi, Alexander Nast   +9 more
wiley   +1 more source

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MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates

Science Translational Medicine, 2020
Inhibiting transgene expression with a tissue-specific microRNA target ameliorates AAV vector toxicity in NHPs. Mitigating gene therapy toxicity Gene therapy using adeno-associated viral (AAV) vectors has shown promising results for treating neurological
J. Hordeaux, E. Buza, B. Jeffrey, Chunjuan Song, Tahsin Jahan, Yuan Yuan, Yanqing Zhu, Peter Bell, Mingyao Li, Jessica A. Chichester, R. Calcedo, James M. Wilson   +11 more
semanticscholar   +1 more source

Transgenic fish

Trends in Biotechnology, 1990
A range of transgenic animal species have been generated using DNA microinjection, and application of this technique to fish is now showing some degree of success. Studies to optimize microinjection techniques specifically for use with fish, and to investigate possible alternative methods for mass culture, should lead to the commercial production of ...
T T, Chen, D A, Powers
openaire   +2 more sources

Transgenic bioreactors

International Journal of Biochemistry, 1994
1. Although many human therapeutic proteins are currently produced in microbial fermentors using recombinant DNA techniques, it is obvious that microbial processing is not suitable for a large number of bioactive proteins owing to the inability of bacteria to carry out postsynthetic modification reactions required for full biological activity. 2.
J, Jänne, J M, Hyttinen, T, Peura, M, Tolvanen, L, Alhonen, R, Sinervirta, M, Halmekytö   +6 more
openaire   +2 more sources