Results 341 to 350 of about 360,625 (378)
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Development, Growth & Differentiation, 2012
The development of transgenic chicken technology has lagged far behind that of mammalian species. Two reasons for this are that only a one‐cell‐stage oocyte can be obtained from a sacrificed hen and that the yolk prevents high‐magnification microscopic observation of oocytes.
Ken-ichi, Nishijima, Shinji, Iijima
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The development of transgenic chicken technology has lagged far behind that of mammalian species. Two reasons for this are that only a one‐cell‐stage oocyte can be obtained from a sacrificed hen and that the yolk prevents high‐magnification microscopic observation of oocytes.
Ken-ichi, Nishijima, Shinji, Iijima
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2016
The generation and use of transgenic animals carrying exogenous pieces of DNA stably integrated in their genome is a quite common practice in modern laboratories. Zebrafish have been increasingly used for transgenesis studies mainly due to easy egg accessibility and manipulation together with relatively short generation time.
Xiaowen, Chen +2 more
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The generation and use of transgenic animals carrying exogenous pieces of DNA stably integrated in their genome is a quite common practice in modern laboratories. Zebrafish have been increasingly used for transgenesis studies mainly due to easy egg accessibility and manipulation together with relatively short generation time.
Xiaowen, Chen +2 more
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BioEssays, 1987
AbstractTransgenic mice constitute an entirely new dimension of mammalian molecular genetics. They allow us to observe genes at work in the intact organism. Virtually every sector of biomedical research is likely to be affected.
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AbstractTransgenic mice constitute an entirely new dimension of mammalian molecular genetics. They allow us to observe genes at work in the intact organism. Virtually every sector of biomedical research is likely to be affected.
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2003
The exact structure of a microinjection transgene depends entirely on the aims of a particular experiment. In this context, reference to the chapters on the applications of transgenesis and technical details of transgenes described in references therein are highly recommended.
Murphy, D., Carter, D.A., Smith, D.R.
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The exact structure of a microinjection transgene depends entirely on the aims of a particular experiment. In this context, reference to the chapters on the applications of transgenesis and technical details of transgenes described in references therein are highly recommended.
Murphy, D., Carter, D.A., Smith, D.R.
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Paediatric Respiratory Reviews, 2006
For the past 20 years researchers have used transgenic mice to help understand the basic mechanisms associated with inherited human and animal diseases. The ability to integrate exogenous genetic information into the mouse genome has revolutionised the analysis of gene function.
Judy M, Hickman-Davis, Ian C, Davis
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For the past 20 years researchers have used transgenic mice to help understand the basic mechanisms associated with inherited human and animal diseases. The ability to integrate exogenous genetic information into the mouse genome has revolutionised the analysis of gene function.
Judy M, Hickman-Davis, Ian C, Davis
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Genome, 1989
Stable integration into the mouse genome of exogenous genetic information has become, over the past few years, a very potent approach for different aspects of biology. It is a common feature that the integrated exogenous gene (the transgene) is expressed properly both spatially and temporally.
Babinet, C. +2 more
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Stable integration into the mouse genome of exogenous genetic information has become, over the past few years, a very potent approach for different aspects of biology. It is a common feature that the integrated exogenous gene (the transgene) is expressed properly both spatially and temporally.
Babinet, C. +2 more
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Trends in Cardiovascular Medicine, 1995
Transgenic mice are important experimental systems for understanding the regulation of gene expression and the function of various gene products within the complex environment of an intact organism. Recombinant genes are introduced into the mouse embryo and their patterns of expression or phenotypic effects are examined.
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Transgenic mice are important experimental systems for understanding the regulation of gene expression and the function of various gene products within the complex environment of an intact organism. Recombinant genes are introduced into the mouse embryo and their patterns of expression or phenotypic effects are examined.
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1998
Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Science, 1988
The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in the organism have allowed the genetic manipulation of animals on an unprecedented scale. The information gained from the use of the transgenic technology is relevant to almost any aspect of modern biology including developmental gene ...
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The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in the organism have allowed the genetic manipulation of animals on an unprecedented scale. The information gained from the use of the transgenic technology is relevant to almost any aspect of modern biology including developmental gene ...
openaire +2 more sources