Results 41 to 50 of about 4,875 (50)
Cowpox Virus: A New and Armed Oncolytic Poxvirus
Molecular Therapy: Oncolytics, 2017 Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. In this study, we are proposing for the first time to evaluate the in vitro and in vivo oncolytic capacities of the Cowpox virus (CPXV). To
Marine Ricordel +11 more
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یافتههای نوین در علوم زیستی, 2020 One of the main strategies to improve plant tolerance is the expression of stress-induced genes, which play a significant role in the ionic balance of plants. SOS3 is one of the important components of SOS-regulated ionic homeostasis pathway.
Elham Mohajel Kazemi +3 more
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In vitro vascularized immunocompetent patient-derived model to test cancer therapies
iScience, 2023 Summary: This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to ...
Hélène Lê +12 more
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MRI of Transgene Expression: Correlation to Therapeutic Gene Expression
Neoplasia: An International Journal for Oncology Research, 2002 Magnetic resonance imaging (MRI) can provide highresolution 3D maps of structural and functional information, yet its use of mapping in vivo gene expression has only recently been explored.
Tomotsugu Ichikawa +7 more
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OncoImmunology, 2019 Pexastimogene devacirepvec (Pexa-Vec) is a vaccinia virus-based oncolytic immunotherapy designed to preferentially replicate in and destroy tumor cells while stimulating anti-tumor immunity by expressing GM-CSF.
M. Moehler +36 more
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Molecular Therapy: Methods & Clinical Development, 2017 Although baculovirus has been used as a safe and convenient gene delivery vector in mammalian cells, baculovirus-mediated transgene expression is less effective in various mammalian cell lines.
Chia-Hung Wang +4 more
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Effects of overexpression of jasmonic acid biosynthesis genes on nicotine accumulation in tobacco
Plant Direct, 2018 Nicotine is naturally synthesized in tobacco roots and accumulates in leaves as a defense compound against herbivory attack. Nicotine biosynthesis pathway has been extensively studied with major genes and enzymes being isolated and functionally ...
Hongxia Chen +5 more
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Veterinární Medicína, 2006 Genetically modified organisms (GMO) become a real constituent of our lives and nowadays, they are commonly introduced into the food chain of people and animals in some states.
R. Pribylova, I. Pavlik, M. Bartos
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Molecular Therapy: Oncolytics, 2023 Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways.
Jeffrey D. Bryant +8 more
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