Results 41 to 50 of about 355,983 (382)
Human Vaccines & Immunotherapeutics, 2018 Pre-clinical models mimicking persistent hepatitis B virus (HBV) expression are seldom, do not capture all features of a human chronic infection and due to their complexity, are subject to variability.
Roland Kratzer +7 more
doaj +1 more source
Compensation of Wild Plants Weakens the Effects of Crop-Wild Gene Flow on Wild Rice Populations
Frontiers in Plant Science, 2021 Crop-wild gene flow may alter the fitness of the recipient i.e., crop-wild hybrids, then potentially impact wild populations, especially for the gene flow carrying selective advantageous crop alleles, such as transgenes conferring insect resistance ...
Dongxin Ouyang +9 more
doaj +1 more source
Transgene Expression in Microalgae—From Tools to Applications
Frontiers in Plant Science, 2016 Microalgae comprise a biodiverse group of photosynthetic organisms that reside in water sources and sediments. The green microalgae Chlamydomonas reinhardtii was adopted as a useful model organism for studying various physiological systems.
Lior Doron, Na’ama Segal, M. Shapira
semanticscholar +1 more source
Frontiers in Genetics, 2022 Cystatin proteins are known to form a superfamily of cysteine protease inhibitors, which play a key role in protein degradation and are related to different physiological processes, such as development and immunity.
Juan Antonio Ramirez Merlano +1 more
doaj +1 more source
Frequent Occurrence of Transgene Deletion in Transgenic Plants
Molecules and Cells, 1998 The status of the transgene in tobacco plants transformed by Agrobacterium was analyzed with PCR. Twelve percent of the transgenic plants with the nptII gene showed different levels of transgene deletion, which was also found in transgenic watermelon (10-30%) and carrot (40-60%).
Kim, YS +4 more
openaire +2 more sources
bioRxiv, 2018 Transgenic mouse lines are routinely employed to label and manipulate distinct cell types. The transgene generally comprises cell-type specific regulatory elements linked to a cDNA encoding a reporter or other proteins.
Mallory A. Laboulaye +4 more
semanticscholar +1 more source
Cowpox Virus: A New and Armed Oncolytic Poxvirus
Molecular Therapy: Oncolytics, 2017 Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. In this study, we are proposing for the first time to evaluate the in vitro and in vivo oncolytic capacities of the Cowpox virus (CPXV). To
Marine Ricordel +11 more
doaj +1 more source
Scientific Reports, 2015 The CRISPR/Cas9 system is becoming an important genome editing tool for crop breeding. Although it has been demonstrated that target mutations can be transmitted to the next generation, their inheritance pattern has not yet been fully elucidated.
R. Xu +9 more
semanticscholar +1 more source
Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]
, 2003 A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM +4 more
core +1 more source
Journal of Cellular and Molecular Medicine, 2017 In our previous study, we demonstrated that episomal vectors based on the characteristic sequence of matrix attachment regions (MARs) and containing the cytomegalovirus (CMV) promoter allow transgenes to be maintained episomally in Chinese hamster ovary (
Xiaoyin Wang +7 more
semanticscholar +1 more source