Results 51 to 60 of about 361,542 (380)

Compensation of Wild Plants Weakens the Effects of Crop-Wild Gene Flow on Wild Rice Populations

open access: yesFrontiers in Plant Science, 2021
Crop-wild gene flow may alter the fitness of the recipient i.e., crop-wild hybrids, then potentially impact wild populations, especially for the gene flow carrying selective advantageous crop alleles, such as transgenes conferring insect resistance ...
Dongxin Ouyang   +9 more
doaj   +1 more source

Engineering of CRISPR/Cas9‐mediated potyvirus resistance in transgene‐free Arabidopsis plants

open access: yesMolecular plant pathology, 2016
Summary Members of the eukaryotic translation initiation factor (eIF) gene family, including eIF4E and its paralogue eIF(iso)4E, have previously been identified as recessive resistance alleles against various potyviruses in a range of different hosts ...
D. E. Pyott, Emma Sheehan, A. Molnár
semanticscholar   +1 more source

A meta-analysis of the antiviral activity of the HBV-specific immunotherapeutic TG1050 confirms its value over a wide range of HBsAg levels in a persistent HBV pre-clinical model

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Pre-clinical models mimicking persistent hepatitis B virus (HBV) expression are seldom, do not capture all features of a human chronic infection and due to their complexity, are subject to variability.
Roland Kratzer   +7 more
doaj   +1 more source

Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes and Neighboring Endogenous Genes

open access: yesbioRxiv, 2018
Transgenic mouse lines are routinely employed to label and manipulate distinct cell types. The transgene generally comprises cell-type specific regulatory elements linked to a cDNA encoding a reporter or other proteins.
Mallory A. Laboulaye   +4 more
semanticscholar   +1 more source

The EF‐1α promoter maintains high‐level transgene expression from episomal vectors in transfected CHO‐K1 cells

open access: yesJournal of Cellular and Molecular Medicine, 2017
In our previous study, we demonstrated that episomal vectors based on the characteristic sequence of matrix attachment regions (MARs) and containing the cytomegalovirus (CMV) promoter allow transgenes to be maintained episomally in Chinese hamster ovary (
Xiaoyin Wang   +7 more
semanticscholar   +1 more source

Cowpox Virus: A New and Armed Oncolytic Poxvirus

open access: yesMolecular Therapy: Oncolytics, 2017
Oncolytic virus therapy has recently been recognized as a promising new therapeutic approach for cancer treatment. In this study, we are proposing for the first time to evaluate the in vitro and in vivo oncolytic capacities of the Cowpox virus (CPXV). To
Marine Ricordel   +11 more
doaj   +1 more source

GmSTK12 Participates in Salt Stress Resistance in Soybean

open access: yesAgronomy, 2023
Soybean (Glycine max (Linn.) Merr.) is a widely-cultivated crop, the yield of which is markedly affected by adverse environmental conditions. Soil salinization, in particular, has led to the degradation of agricultural land, resulting in poor plant ...
Yang Liu   +8 more
doaj   +1 more source

Transgene Expression in Microalgae—From Tools to Applications

open access: yesFrontiers in Plant Science, 2016
Microalgae comprise a biodiverse group of photosynthetic organisms that reside in water sources and sediments. The green microalgae Chlamydomonas reinhardtii was adopted as a useful model organism for studying various physiological systems.
Lior Doron, Na’ama Segal, M. Shapira
semanticscholar   +1 more source

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

open access: yesScientific Reports, 2016
Gene therapy for cystic fibrosis using non-viral, plasmid-based formulations has been the subject of intensive research for over two decades but a clinically viable product has yet to materialise in large part due to inefficient transgene expression ...
M. Munye   +6 more
semanticscholar   +1 more source

Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system [PDF]

open access: yes, 2016
BACKGROUND: Eimeria species are parasitic protozoa that cause coccidiosis, an intestinal disease commonly characterised by malabsorption, diarrhoea and haemorrhage that is particularly important in chickens.
Blake, D P   +6 more
core   +3 more sources

Home - About - Disclaimer - Privacy