Results 81 to 90 of about 360,625 (378)
Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue
Advanced Healthcare Materials, EarlyView.Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri +6 more
wiley +1 more source
Green Fluorescent Protein (GFP) in Vector Systems Played Sense Role of Epigenetic in Plants [PDF]
, 2008 The green fluorescent protein (GFP) of jellyfish (_Aequorea victoria_) has significant advantages over other reporter genes, because expression can be detected in living cells without any substrates.
Hany A. El-Shemy +2 more
core +1 more source
Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]
, 2003 A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche +8 more
wiley +1 more source
Molecular Therapy: Oncolytics, 2023 Oncolytic viruses (OVs) promote the anti-tumor immune response as their replication, and the subsequent lysis of tumor cells, triggers the activation of immune-sensing pathways.
Jeffrey D. Bryant +8 more
doaj +1 more source
Journal of Andrology, 1997 There are numerous tools available to modify the genetic makeup of animals. They are being used to good advantage for studying basic biological phenomena. Within the decade, biomedical products derived from transgenic animals will be available, but the use of this technology for enhancing the quality and efficiency of livestock production will await ...
Wall, R. J. +4 more
openaire +3 more sources
Assessment of pollen-mediated transgene flow in citrus under experimental field conditions [PDF]
, 2015 Despite potential benefits granted by genetically modified (GM) citrus trees, their release and commercialization raises concerns about their potential environmental impact.
Navarro, Antonio +3 more
core
Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones [PDF]
, 2011 Peer reviewedPublisher ...
Davidson, Scott +4 more
core +4 more sources
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
Nature Methods, 2009 Induced pluripotent stem cells (iPSCs) have been generated from somatic cells by transgenic expression of Oct4 (Pou5f1), Sox2, Klf4 and Myc. A major difficulty in the application of this technology for regenerative medicine, however, is the delivery of ...
K. Yusa, R. Rad, J. Takeda, A. Bradley
semanticscholar +1 more source
Hippocampal Chandelier Cells Modulate Seizure Susceptibility and Severity
Advanced Science, EarlyView.The axon initial segment (AIS), crucial for action potential initiation, serves as a prime locus for controlling network activity. Chandelier Cells (ChCs), evolved in the mammals, intricately target AISs, acting as gatekeepers for neuronal firing. Diminishing ChC input makes animals more prone to developing seizures, whereas fortifying this connection ...
Yang Li +7 more
wiley +1 more source