Results 191 to 200 of about 17,268 (246)
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Distinctions between transgenerational and non-transgenerational epimutations
Molecular and Cellular Endocrinology, 2014Recent studies have described numerous environmentally-induced disruptions of the epigenome (epimutations) in mammals. While some of these appear to be corrected by normal germline-specific epigenetic reprogramming and are therefore not transmitted transgenerationally, others are not corrected and are transmitted over multiple subsequent generations ...
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Transgenerational Epigenetic Inheritance
Annual Review of Genetics, 2018Inheritance of genomic DNA underlies the vast majority of biological inheritance, yet it has been clear for decades that additional epigenetic information can be passed on to future generations. Here, we review major model systems for transgenerational epigenetic inheritance via the germline in multicellular organisms. In addition to surveying examples
Oliver Rando, Ana Boskovic
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Transgenerational Health Promotion
Holistic Nursing Practice, 2000The Adult Health and Development Program (AHDP) is an intergenerational, interdisciplinary health promotion and rehabilitation program in which nursing and other college students are paired with older adults to engage in activities to improve their health and well-being.
N, Watson, L, Pulliam
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Plant Transgenerational Epigenetics
Annual Review of Genetics, 2016Transgenerational epigenetics is defined in opposition to developmental epigenetics and implies an absence of resetting of epigenetic states between generations. Unlike mammals, plants appear to be particularly prone to this type of inheritance. In this review, we summarize our knowledge about transgenerational epigenetics in plants, which entails ...
Leandro, Quadrana, Vincent, Colot
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Transgenerational Effects of NMs
2014Nanomaterials are present in a number of commercially available products but there are uncertainties as to whether the unique properties that support their commercial use may also pose potential health risks. Information is missing concerning the influence of nanomaterials on the overall reproductive outcome and transgenerational effects in animals and
POMA, Anna Maria Giuseppina +3 more
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Epigenetic Transgenerational Inheritance
2019Epigenetic information refers to heritable changes in gene expression that occur without modifications at the DNA sequence level. These changes are orchestrated by different epigenetic mechanisms such as DNA methylation, posttranslational modifications of histones, and the presence of noncoding RNAs. Epigenetic information regulates chromatin structure
Joan, Blanco Rodríguez +1 more
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Transgenerational PCOS transmission
Nature Medicine, 2019There is a transgenerational increase in the susceptibility of female offspring to developing PCOS that occurs via the female germline and is linked to fetal exposure to excess androgen.
H M, Picton, A H, Balen
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