Results 261 to 270 of about 80,448 (304)
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Development, Growth & Differentiation, 2012
The development of transgenic chicken technology has lagged far behind that of mammalian species. Two reasons for this are that only a one‐cell‐stage oocyte can be obtained from a sacrificed hen and that the yolk prevents high‐magnification microscopic observation of oocytes.
Ken-ichi, Nishijima, Shinji, Iijima
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The development of transgenic chicken technology has lagged far behind that of mammalian species. Two reasons for this are that only a one‐cell‐stage oocyte can be obtained from a sacrificed hen and that the yolk prevents high‐magnification microscopic observation of oocytes.
Ken-ichi, Nishijima, Shinji, Iijima
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Trends in Biotechnology, 1990
A range of transgenic animal species have been generated using DNA microinjection, and application of this technique to fish is now showing some degree of success. Studies to optimize microinjection techniques specifically for use with fish, and to investigate possible alternative methods for mass culture, should lead to the commercial production of ...
T T, Chen, D A, Powers
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A range of transgenic animal species have been generated using DNA microinjection, and application of this technique to fish is now showing some degree of success. Studies to optimize microinjection techniques specifically for use with fish, and to investigate possible alternative methods for mass culture, should lead to the commercial production of ...
T T, Chen, D A, Powers
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Genome, 1989
Stable integration into the mouse genome of exogenous genetic information has become, over the past few years, a very potent approach for different aspects of biology. It is a common feature that the integrated exogenous gene (the transgene) is expressed properly both spatially and temporally.
Babinet, C. +2 more
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Stable integration into the mouse genome of exogenous genetic information has become, over the past few years, a very potent approach for different aspects of biology. It is a common feature that the integrated exogenous gene (the transgene) is expressed properly both spatially and temporally.
Babinet, C. +2 more
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Science, 1988
The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in the organism have allowed the genetic manipulation of animals on an unprecedented scale. The information gained from the use of the transgenic technology is relevant to almost any aspect of modern biology including developmental gene ...
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The ability to introduce foreign genes into the germ line and the successful expression of the inserted gene in the organism have allowed the genetic manipulation of animals on an unprecedented scale. The information gained from the use of the transgenic technology is relevant to almost any aspect of modern biology including developmental gene ...
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Trends in Cardiovascular Medicine, 1995
Transgenic mice are important experimental systems for understanding the regulation of gene expression and the function of various gene products within the complex environment of an intact organism. Recombinant genes are introduced into the mouse embryo and their patterns of expression or phenotypic effects are examined.
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Transgenic mice are important experimental systems for understanding the regulation of gene expression and the function of various gene products within the complex environment of an intact organism. Recombinant genes are introduced into the mouse embryo and their patterns of expression or phenotypic effects are examined.
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1998
Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Since the generation of the first transgenic mice in 1980, transgene technology has also been successfully applied to large farm animals. Although this technology can be employed to improve certain production traits of livestock, this approach has not been very successful so far owing to unwanted effects encountered in the production animals.
J, Jänne +5 more
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Cloning a Transgene for Transgenic RNAi in Mouse Oocytes
Cold Spring Harbor Protocols, 2009INTRODUCTIONRNA interference (RNAi) is a suitable method for sequence-specific post-transcriptional gene silencing for many model systems. The protocol presented here describes the cloning of a plasmid construct for use in transgenic RNAi experiments in mouse oocytes. The protocol is intended for production of a transgene by cloning an inverted repeat (
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Transgene Methylation in Transgenic Animals
2022Kenneth J. Snibson, Timothy E. Adams
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