Results 161 to 170 of about 2,431,271 (378)

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

Neurobiology of Disease, 2011
Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disease caused by polyglutamine-expanded ataxin-3. Previously, we prepared a SCA3 animal model by generating transgenic mice expressing disease-causing ataxin-3-Q79.
An-Hsun Chou, Si-Ying Chen, Tu-Hsueh Yeh, Yi-Hsin Weng, Hung-Li Wang   +4 more
doaj  

Hepatitis B surface antigen gene expression is regulated by sex steroids and glucocorticoids in transgenic mice.

, 1987
Hend Farza, A.-M. Salmon, Michelle Hadchouel, Jean‐Luc Moreau, Charles Babinet, Pierre Tiollais, Christine Pourcel   +6 more
openalex   +1 more source

Expression of the human growth hormone variant gene in cultured fibroblasts and transgenic mice. [PDF]

, 1988
Richard F. Selden, Thomas E. Wagner, Sandra L. Blethen, June Yun, Mary Ellen Rowe, H. M. Goodman   +5 more
openalex   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Immunological function of HLA-C antigens in HLA-Cw3 transgenic mice.

, 1988
Othmar Dill, Femia Kievits, Sven D. Koch, P Iványi, G J Hämmerling   +4 more
openalex   +1 more source

Recognition of xeno-(HLA, SLA) major histocompatibility complex antigens by mouse cytotoxic T cells is not H-2 restricted: a study with transgenic mice. [PDF]

, 1989
Femia Kievits, Josien F.A.M. Wijffels, W. Lokhorst, P. Iványi   +3 more
openalex   +1 more source

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

Neuron, 2015
L. Madisen, Aleena R. Garner, Daisuke Shimaoka, A. Chuong, Nathan C. Klapoetke, Lu Li, A. Bourg, Y. Niino, Ladan Egolf, C. Monetti, Hong Gu, Maya Mills, A. Cheng, Bosiljka Tasic, T. Nguyen, S. Sunkin, A. Benucci, A. Nagy, A. Miyawaki, F. Helmchen, R. Empson, T. Knöpfel, E. Boyden, R. Reid, M. Carandini, Hongkui Zeng   +25 more
semanticscholar   +1 more source

Divergent disease patterns in granulocyte-macrophage colony-stimulating factor transgenic mice associated with different transgene insertion sites. [PDF]

, 1988
D Metcalf, Jeffrey G. Moore
openalex   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source