Results 201 to 210 of about 1,952,729 (355)

Novel Bedding Material Results in Poor Pregnancy Rate with CD-1 Female Mice Used as Fosters for Producing Transgenic Mice

, 2017
Jussi Helppi, Ronald Naumann, Marianne Asikainen, J. Mononen, Oliver Zierau   +4 more
openalex   +2 more sources

Supplementary Data from HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy–Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout Mice

, 2023
Elin M.V. Forsberg, Mattias F. Lindberg, Henrik Jespersen, Samuel Alsén, Roger Olofsson Bagge, Marco Donia, Inge Marie Svane, Ola Nilsson, Lars Ny, Lisa M. Nilsson, Jonas A. Nilsson   +10 more
openalex   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Substitution of histidine 95 by tyrosine in the prion protein causes spontaneous neurodegeneration in transgenic mice. [PDF]

PLoS Pathog
Torres JM, Marín-Moreno A, Espinosa JC, Canoyra S, Burato A, Ciullini A, De Luca CMG, Bistaffa E, Moda F, Legname G.   +9 more
europepmc   +1 more source

The effects of β-sheet breaker peptide-H102 on APP transgenic mice

, 2011
Xiangyu BO, Man WANG, Kaijun ZHENG, Yanling Xu, Huijuan CHAI, Laixiang LIN, Shumei Xu, Jinyan He, Xiangyu BO, Ming Song, Yuanzhen Tan, Juan Zhao, Zhihong Ma, Deyong DONG, Mei Li   +14 more
openalex   +1 more source

Identification and Mechanisms of Osteocyte Subsets Involved in the Pathological Progression of Osteoporosis

Advanced Science, EarlyView.
Osteocyte heterogeneity in bone remains poorly understood. This study identifies six distinct osteocyte subsets in mice, revealing a key subpopulation (BHR‐Ocys) that drives bone loss in osteoporosis. BHR‐Ocys promote osteoclast‐mediated resorption via a novel Sema5a‐Plxna1 signaling axis.
Zengxin Jiang, Biyu Rui, Xuecheng He, Jiajun Wang, Xiangdong Wu, Rui Shao, Xue Meng, Xiaochun Peng, Hengfeng Yuan   +8 more
wiley   +1 more source

Tissue-specific consequences of tag fusions on protein expression in transgenic mice. [PDF]

PLoS Genet
Taylor GCA, Macdonald L, Szulc NA, Gudauskaite E, Hernandez Moran B, Brisbane JM, Donald M, Taylor E, Zheng D, Gu B, Mill P, Yeyati PL, Pokrzywa W, Ribeiro de Almeida C, Wood AJ.   +14 more
europepmc   +1 more source

Histological Analysis of Beta-Amyloid (Aβ) and Metal Ion Aggregation into Neuritic Plaques in Tg2576 Transgenic Mice

, 2011
Everett-Teejay Brown
openalex   +1 more source

Superiority of thyroid peroxidase DNA over protein immunization in replicating human thyroid autoimmunity in HLA-DRB1*0301 (DR3) transgenic mice [PDF]

, 2004
Jeffrey C. Flynn, A Gardas, Qiang Wan, Monika Góra, Ghazwan Alsharabi, Wenjing Wei, Alvaro A. Giraldo, Chella S. David, Yi‐chi M. Kong, J. Paul Banga   +9 more
openalex   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source