Results 221 to 230 of about 1,712,319 (264)

Insertional mutagenesis in transgenic mice

Transgenic Research, 1994
Increasing numbers of transgenic mouse lines have resulted in several dozens of mutants created by insertional mutagenesis. The advantages of different vector systems and the problems associated with the analysis of mutations and the cloning of the affected genes are discussed in this review.
T, Rijkers, A, Peetz, U, Rüther
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Transgenic mice

Cell, 1985
R D, Palmiter, R L, Brinster
openaire   +2 more sources

Histological Examination of Transgenic Mice

2003
Histological examination is important to detect and differentiate among different types of tissue changes at the microscopic level. An enlarged organ can be hyperplastic, hypertrophied, or neoplastic. It can also be merely inflamed or infected. Only a histological examination can differentiate among the various growth disturbances and pathological ...
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Transgenic RNA Interference in Mice

2008
RNA interference (RNAi) is a powerful tool in deciphering gene function. It has been used extensively, especially in cultured mammalian cells. We have shown that RNAi-induced gene silencing can be generated in mice. With conventional transgenic techniques, shRNA-expressing constructs can be introduced into one-cell mouse embryos. The transgenic animals
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Oncogenes in transgenic mice

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1988
S J, Compere, P, Baldacci, R, Jaenisch
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Postmortem Examination of Transgenic Mice

2003
Postmortem examination of transgenic animals should ideally be performed by or with the help of a trained pathologist. This is because although the steps in the examination can be manually performed by anyone, the interpretation of the findings can only be done with the knowledge of veterinary medicine.
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Analysis of Transgenic Mice

2003
Stefan, Selbert, Dominic, Rannie
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Transgenic Mice and Hemoglobinopathies

2003
Mary E, Fabry, Eric E, Bouhassira, Sandra M, Suzuka, Ronald L, Nagel   +3 more
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Generation of Transgenic Mice

2003
M H, Hofker, M, Breuer
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Transgenic Mice

Otolaryngologic Clinics of North America, 1992
Rick A. Friedman, Allen F. Ryan
openaire   +1 more source