Results 241 to 250 of about 1,644,173 (317)

Synergistic drug combination screening using a nanodroplet processing platform to enhance neuroblastoma treatment in TH-MYCN transgenic mice. [PDF]

Bioeng Transl Med
Liao YT, Yu ZK, Huang YX, Lin KH, Kuo CT, Yang TS, Wu PY, Yeh CT, Liu YL, Chen CC, Chen CN, Hsu WM, Lee H.   +12 more
europepmc   +1 more source

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang, Luju Jiang, Shuqi Cai, Zheqi Weng, Yuheng Zhu, Zhi‐Wei Cai, Hui Li, Qing Li, Li‐Peng Hu, Hong‐Fei Yao, Rong Hua, Yu Zhao, Dongxue Li, Xiao‐Mei Yang, Jun‐Feng Zhang, Shu‐Heng Jiang   +15 more
wiley   +1 more source

Transgenic mice applications in the study of endometriosis pathogenesis. [PDF]

Front Cell Dev Biol
Zhao Y, Wang Y, Gu P, Tuo L, Wang L, Jiang SW.   +5 more
europepmc   +1 more source

Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial‐Neural Axis

Advanced Science, EarlyView.
The authors develop mouse models by mimicking peripheral vascular diseases, combining multiple strategies and transgenic mouse lines, to demonstrate that ECs, but not macrophages or SMCs, play an active role mediated by endothelial ET‐1/neural ETAR signaling and beyond endothelial homeostatic angiocrine by driving protective pain through the ...
Zuo‐Jie Jiang, Di Mu, Su Liu, Peng‐Bo Jing, Bin Wu, Xiao‐Mei Yang, Jia‐Yi Ge, Qing‐Yi Li, Hao‐Hao Chen, Feng‐Ming Zhang, Bing Wang, Ying‐Ying Zhang, Linnan Qian, Zi‐Yi Zhu, Yu‐Sen Ou, Shi‐Yu Sun, Lin Luo, Yu Feng, Changyu Jiang, Zhuo Sun, Yong Chen, Hai‐Li Pan, Bin Wang, Fen‐Fei Gao, Jie Wu, Zhigang Lu, Tong Liu, Yan‐Gang Sun, Xing‐Jun Liu   +28 more
wiley   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source

Effects of Psilocin and Psilocybin on Human 5-HT₄ Serotonin and H₂ Histamine Receptors in Perfused Hearts of Transgenic Mice. [PDF]

Pharmaceuticals (Basel)
Braekow P, Neumann J, Kirchhefer U, Gergs U.   +3 more
europepmc   +1 more source

Neuroprotective role of sialic-acid-binding immunoglobulin-like lectin-11 in humanized transgenic mice. [PDF]

Front Neurosci
Abou Assale T, Afrang N, Wissfeld J, Cuevas-Rios G, Klaus C, Linnartz-Gerlach B, Neumann H.   +6 more
europepmc   +1 more source

Pathophysiologic abnormalities in transgenic mice carrying the Alzheimer disease PSEN1 Δ440 mutation. [PDF]

Hum Mol Genet
Fuller PE, Collis VL, Sharma P, Burkett AM, Wang S, Brown KA, Weir N, Goulbourne CN, Nixon RA, Longden TA, Gould TD, Monteiro MJ.   +11 more
europepmc   +1 more source

Silencing of the von Willebrand factor gene in proatherothrombotic <i>APOE∗3-Leiden.CETP</i> transgenic mice. [PDF]

Res Pract Thromb Haemost
Jongejan YK, Dirven RJ, Schrader Echeverri E, de Jong AJL, Pronk ACM, Kooijman S, Rensen PCN, Dahlman JE, Eikenboom JCJ, van Vlijmen BJM.   +9 more
europepmc   +1 more source

Inflammatory Stimuli and Fecal Microbiota Transplantation Accelerate Pancreatic Carcinogenesis in Transgenic Mice, Accompanied by Changes in the Microbiota Composition. [PDF]

Cells
Świdnicka-Siergiejko A, Daniluk J, Miniewska K, Daniluk U, Guzińska-Ustymowicz K, Pryczynicz A, Dąbrowska M, Rusak M, Ciborowski M, Dąbrowski A.   +9 more
europepmc   +1 more source