Results 301 to 310 of about 3,746,688 (357)

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Science, 1996
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, Fusheng Yang, G. Cole   +7 more
semanticscholar   +1 more source

Histological Examination of Transgenic Mice

2003
Histological examination is important to detect and differentiate among different types of tissue changes at the microscopic level. An enlarged organ can be hyperplastic, hypertrophied, or neoplastic. It can also be merely inflamed or infected. Only a histological examination can differentiate among the various growth disturbances and pathological ...
openaire   +2 more sources

Transgenic mice and the pathogenesis of poliomyelitis

1994
Transgenic mice expressing the cell receptor for poliovirus have been generated and are susceptible to poliovirus infection. TgPVR mice have been used to answer questions about the pathogenesis of poliovirus infection. Despite the widespread pattern of PVR expression, poliovirus infection in TgPVR mice is restricted to only a few sites, indicating that
V R, Racaniello, R, Ren
openaire   +2 more sources

Transgenic RNA Interference in Mice

2008
RNA interference (RNAi) is a powerful tool in deciphering gene function. It has been used extensively, especially in cultured mammalian cells. We have shown that RNAi-induced gene silencing can be generated in mice. With conventional transgenic techniques, shRNA-expressing constructs can be introduced into one-cell mouse embryos. The transgenic animals
openaire   +2 more sources

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Nature, 1995
D. Games, David John Adams, Ree Alessandrini, R. Barbour, Patricia Borthelette, C. Blackwell, Tony Carr, J. Clemens, T. Donaldson, F. Gillespie, T. Guido, S. Hagopian, K. Johnson-wood, K. Khan, Mike Lee, P. Leibowitz, I. Lieberburg, S. Little, E. Masliah, L. McConlogue, M. Montoya-Zavala, L. Mucke, L. Paganini, E. Penniman, M. Power, D. Schenk, P. Seubert, B. Snyder, F. Soriano, H. Tan, J. Vitale, S. Wadsworth, B. Wolozin, Jun Zhao   +33 more
semanticscholar   +1 more source

Oncogenes in transgenic mice

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1988
S J, Compere, P, Baldacci, R, Jaenisch
openaire   +2 more sources

Postmortem Examination of Transgenic Mice

2003
Postmortem examination of transgenic animals should ideally be performed by or with the help of a trained pathologist. This is because although the steps in the examination can be manually performed by anyone, the interpretation of the findings can only be done with the knowledge of veterinary medicine.
openaire   +2 more sources

Analysis of Transgenic Mice

2003
Stefan, Selbert, Dominic, Rannie
openaire   +2 more sources

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Science, 2001
Jada Lewis, D. Dickson, Wen‐lang Lin, L. Chisholm, A. Corral, G. Jones, S. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton, E. McGowan   +13 more
semanticscholar   +1 more source

Transgenic Mice and Hemoglobinopathies

2003
Mary E, Fabry, Eric E, Bouhassira, Sandra M, Suzuka, Ronald L, Nagel   +3 more
openaire   +2 more sources