Results 341 to 350 of about 3,709,047 (395)

Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP

Science, 2001
Jada Lewis, D. Dickson, Wen‐lang Lin, L. Chisholm, A. Corral, Graham Jones, S. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton, E. McGowan   +13 more
semanticscholar   +1 more source

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

Nature Genetics, 2003
D. Rubinson, C. Dillon, A. Kwiatkowski, C. Sievers, Lili Yang, J. Kopinja, Dina L Rooney, Mingdi Zhang, M. Ihrig, Michael T. McManus, F. Gertler, M. Scott, L. Parijs   +12 more
semanticscholar   +1 more source

Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Aβ42 Fibrils

Science, 2001
J. Götz, Feng Chen, J. Dorpe, R. Nitsch
semanticscholar   +1 more source

Transgenic RNA Interference in Mice

2008
RNA interference (RNAi) is a powerful tool in deciphering gene function. It has been used extensively, especially in cultured mammalian cells. We have shown that RNAi-induced gene silencing can be generated in mice. With conventional transgenic techniques, shRNA-expressing constructs can be introduced into one-cell mouse embryos. The transgenic animals
openaire   +2 more sources

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

Nature, 1985
Jerry M. Adams, A. W. Harris, C. Pinkert, L. Corcoran, W. Alexander, S. Cory, R. Palmiter, R. Brinster   +7 more
semanticscholar   +1 more source

Transgenic Mice

2001
Lina Mullen, Allen Ryan
openaire   +1 more source

Oncogenes in transgenic mice

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1988
S J, Compere, P, Baldacci, R, Jaenisch
openaire   +2 more sources

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

Nature, 1988
C. Goodnow, J. Crosbie, S. Adelstein, T. Lavoie, S. Smith‐Gill, R. Brink, H. Pritchard-Briscoe, J. Wotherspoon, R. Loblay, Kathy Raphael, R. Trent, A. Basten   +11 more
semanticscholar   +1 more source

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Nature Medicine, 1998
L. Holcomb, M. Gordon, E. McGowan, Xin Yu, S. Benkovic, P. Jantzen, K. Wright, Irene Saad, R. Mueller, D. Morgan, S. Sanders, C. Zehr, Kassandra O'Campo, J. Hardy, C. Prada, C. Eckman, S. Younkin, K. Hsiao, K. Duff   +18 more
semanticscholar   +1 more source

Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development

Signal Transduction and Targeted Therapy, 2021
Miao-Miao Zhao, Wei-Li Yang, Wei-jin Huang   +2 more
exaly