Results 181 to 190 of about 332,647 (335)

The splicing genes SmEa and SmEb regulate plant development during vegetative growth in poplar. [PDF]

BMC Plant Biol
Goretti D, Collani S, Marcon A, Nilsson O, Schmid M.   +4 more
europepmc   +1 more source

Yeast profilin complements profilin deficiency in transgenic tomato fruits and allows development of hypoallergenic tomato fruits [PDF]

, 2010
Lien Quynh Le, Vera Mahler, Stephan Scheurer, Kay Foetisch, Yvonne Braun, Daniela Weigand, Ernesto Enrique, Jonas Lidholm, Kathrin E. Paulus, Sophia Sonnewald, Stefan Vieths, Uwe Sonnewald   +11 more
openalex   +1 more source

LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.

Human Molecular Genetics, 1998
K. Peterson, P. Navas, Q. Li, G. Stamatoyannopoulos   +3 more
semanticscholar   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Time to bloom: GmREM16a promotes flowering time in soybeans. [PDF]

Plant Physiol
Singh Yadav A.
europepmc   +1 more source

(Over)correction of FMR1 deficiency with YAC transgenics: behavioral and physical features.

Human Molecular Genetics, 2000
A. Peier, K. L. McIlwain, A. Kenneson, S. Warren, R. Paylor, D. Nelson   +5 more
semanticscholar   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2. [PDF]

PLoS Genet
Jochim B, Topalidou I, Lehrbach N.
europepmc   +1 more source

Characterization of the cytosolic and mitochondrial glutathione redox potential using cardiomyocyte specific transgenic Grx1-roGFP2 sensor mice

, 2023
Andrea Fecke
openalex   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source