Results 11 to 20 of about 14,093 (261)

Coexpression of GSK-3β Corrects Phenotypic Aberrations of Dorsal Root Ganglion Cells, Cultured from Adult Transgenic Mice Overexpressing Human Protein tau

Neurobiology of Disease, 2002
Coexpression of constitutively active GSK-3β[S9A] rescued the axonal pathology induced by overexpression of human tau in transgenic mice (Spittaels et al., (2000) J. Biol. Chem. 275, 41340–41349).
R. Nuydens, G. Van Den Kieboom, C. Nolten, C. Verhulst, P. Van Osta, K. Spittaels, C. Van den Haute, E. De Feyter, H. Geerts, F. Van Leuven   +9 more
doaj   +1 more source

A Sugarcane G-Protein-Coupled Receptor, ShGPCR1, Confers Tolerance to Multiple Abiotic Stresses

Frontiers in Plant Science, 2021
Sugarcane (Saccharum spp.) is a prominent source of sugar and serves as bioenergy/biomass feedstock globally. Multiple biotic and abiotic stresses, including drought, salinity, and cold, adversely affect sugarcane yield.
Manikandan Ramasamy, Mona B. Damaj, Carol Vargas-Bautista, Victoria Mora, Jiaxing Liu, Carmen S. Padilla, Sonia Irigoyen, Tripti Saini, Nirakar Sahoo, Jorge A. DaSilva, Jorge A. DaSilva, Kranthi K. Mandadi, Kranthi K. Mandadi   +12 more
doaj   +1 more source

Gene Discovery and Advances in Finger millet [Eleusine coracana (L.) Gaertn.] Genomics - An Important Nutri-cereal of Future

Frontiers in Plant Science, 2016
The rapid strides in molecular marker technologies followed by genomics, and next generation sequencing advancements in three major crops (rice, maize and wheat) of the world have given opportunities for their use in the orphan, but highly valuable ...
Salej Sood, Anil Kumar, Kalyan B Babu, Kalyan B Babu, Vikram Singh Gaur, Vikram Singh Gaur, Dinesh Pandey, Lakshmi Kant, Arunava Pattanayak   +8 more
doaj   +1 more source

Avaliação qualitativa e quantitativa da microbiota do solo e da fixação biológica do nitrogênio pela soja Quantitative and qualitative evaluations of soil microbes and biological nitrogen fixation in soybean

Pesquisa Agropecuária Brasileira, 2008
O objetivo deste trabalho foi definir, para as condições edafoclimáticas do Brasil, níveis aceitáveis de dispersão de alguns parâmetros biológicos, utilizados em estudos de impacto ambiental de novas tecnologias usadas na cultura da soja.
Rosinei Aparecida de Souza, Mariangela Hungria, Julio Cezar Franchini, Ligia Maria de Oliveira Chueire, Fernando Gomes Barcellos, Rubens José Campo   +5 more
doaj   +1 more source

F-Box Family Genes, LTSF1 and LTSF2, Regulate Low-Temperature Stress Tolerance in Pepper (Capsicum chinense)

Plants, 2020
The F-box proteins belong to a family of regulatory proteins that play key roles in the proteasomal degradation of other proteins. Plant F-box proteins are functionally diverse, and the precise roles of many such proteins in growth and development are ...
Jelli Venkatesh, Min-Young Kang, Li Liu, Jin-Kyung Kwon, Byoung-Cheorl Kang   +4 more
doaj   +1 more source

Genetic Transformation of Artemisia carvifolia Buch with rol Genes Enhances Artemisinin Accumulation. [PDF]

PLoS ONE, 2015
The potent antimalarial drug artemisinin has a high cost, since its only viable source to date is Artemisia annua (0.01-0.8% DW). There is therefore an urgent need to design new strategies to increase its production or to find alternative sources. In the
Erum Dilshad, Rosa Maria Cusido, Karla Ramirez Estrada, Mercedes Bonfill, Bushra Mirza   +4 more
doaj   +1 more source

Improved shoot regeneration, salinity tolerance and reduced fungal susceptibility in transgenic tobacco constitutively expressing PR-10a gene

Frontiers in Plant Science, 2016
Plants in ecosystems are simultaneously exposed to abiotic and biotic stresses, which restrict plant growth and development. The complex responses to these stresses are largely regulated by plant hormones, which in turn, orchestrate the different ...
Parinita eAgarwal, Mitali eDabi, Prashant eMore, Khantika ePatel, Kalyanashis eJana, Pradeep K Agarwal   +5 more
doaj   +1 more source

Genetic modelling of PIM proteins in cancer: proviral tagging, cooperation with oncogenes, tumor suppressor genes and carcinogens.

Frontiers in Oncology, 2014
The PIM proteins, which were initially discovered as proviral insertion sites in Moloney murine leukemia virus infection, are a family of highly homologous serine/threonine kinases that have been reported to be overexpressed in hematological malignancies
Enara eAguirre, Oliver eRenner, Maja eNarlik-Grassow, Carmen eBlanco Aparicio   +3 more
doaj   +1 more source

Functional Analysis of Polyprenyl Diphosphate Synthase Genes Involved in Plastoquinone and Ubiquinone Biosynthesis in Salvia miltiorrhiza

Frontiers in Plant Science, 2019
Polyprenyl diphosphate synthase (PPS) plays important roles in the biosynthesis of functionally important plastoquinone (PQ) and ubiquinone (UQ). However, only few plant PPS genes have been functionally characterized.
Miaomiao Liu, Yimian Ma, Qing Du, Qing Du, Xuemin Hou, Meizhen Wang, Shanfa Lu   +6 more
doaj   +1 more source

Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis

Frontiers in Cell and Developmental Biology, 2021
To investigate the effects and mechanisms of irisin, a newly discovered myokine, in cartilage development, osteoarthritis (OA) pathophysiology and its therapeutic potential for treating OA we applied the following five strategical analyses using (1 ...
Xiangfen Li, Xiangfen Li, Xiaofang Zhu, Hongle Wu, Hongle Wu, Thomas E. Van Dyke, Thomas E. Van Dyke, Xiaoyang Xu, Elise F. Morgan, Wenyu Fu, Wenyu Fu, Chuanju Liu, Chuanju Liu, Qisheng Tu, Dingming Huang, Jake Chen   +15 more
doaj   +1 more source