Advanced Science, EarlyView.The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
Machine learning techniques based multi-parameter analysis and design of nonlinear helical structures considering internal structure collisions. [PDF]
Sci RepGu Z, Liu Y, Kong X, Ding X, Hou X.
europepmc +1 more source
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Advanced Science, EarlyView.Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
Modelling, analysis, and stability assessment of wind turbine generator connected to a low inertia AC-DC microgrid with frequency support capability. [PDF]
Sci RepZenhom IA, Marei MI, Mohamed AMI.
europepmc +1 more source
Thermally Induced Creep and Viscoelastic Behavior of Copper Micropillar Arrays
Advanced Science, EarlyView.Copper micropillar arrays are fabricated by electrodeposition within through‐glass‐via, and their thermally induced time‐dependent deformation is quantified. Nanoindentation creep, EBSD, and TEM reveal a heat‐treatment‐driven transition between grain‐boundary‐mediated deformation and dislocation‐dominated creep, while Kelvin modeling captures ...
Miao Wang +14 more
wiley +1 more source
On vibration suppression of a tendon-driven soft robotic neck for the social robot HARU. [PDF]
Front Robot AIThorapalli Muralidharan S +2 more
europepmc +1 more source
Advanced Science, EarlyView.ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao +12 more
wiley +1 more source
A Review of Pavement Damping Characteristics for Mitigating Tire-Pavement Noise: Material Composition and Underlying Mechanisms. [PDF]
Materials (Basel)Liu M, Duan W, Dong R, Al-Ammari M.
europepmc +1 more source
Advanced Science, EarlyView.A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen +5 more
wiley +1 more source
A phase correction frequency selector for enhanced switching accuracy in SH-ADD semi-active suspension. [PDF]
Sci RepZhao J, Su F, Feng J, Fan W, Zhuang Y.
europepmc +1 more source