Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A transient-preserving audio time-stretching algorithm and a real-time realization for a commercial music product [PDF]
, 2012 The core of this work is a sub-band transient detection/preservation scheme based on the complex domain transient detection, and inspired by Robel’s work.
Altoè, Alessandro
core
Instantaneous frequency estimation using the cross Wigner-Ville distribution with application to nonstationary transient detection [PDF]
, 1990 : A method based on an iterative procedure incorporating time-frequency distributions (TFDs) is proposed for instantaneous frequency (IF) estimation of rapidly time-varying signals.
Boashash, Boualem, O'Shea, Peter J.
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The First Photometric Evidence of a Transient/Variable Source at z > 5 with JWST
The Astrophysical JournalThe James Webb Space Telescope (JWST) discovered 79 transients out to z ∼ 4.8 through the JADES Transient Survey (JTS), but the JTS did not find any z > 5 transients.
Christa DeCoursey +29 more
doaj +1 more source
Research on Characteristics of ECVT for Power Quality Detection and Optimum Design of Its Parameter
Energies, 2019 Electronic Capacitive Voltage Transformer (ECVT), connecting the transmission system and measuring device, is the key equipment of digital substation in the distribution network.
Xingjie Liu +3 more
doaj +1 more source
Detecting and Correcting False Transients in Calcium Imaging [PDF]
Nature Methods, 2018 Abstract Population recordings of calcium activity are a major source of insight into neural function. Large dataset sizes often require automated methods, but automation can introduce errors that are difficult to detect. Here we show that automatic time course estimation can sometimes lead to significant misattribution errors, in which
Jeffrey L. Gauthier +5 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Transformer-based Neural Network for Transient Detection without Image Subtraction
The Astronomical JournalWe introduce a transformer-based neural network for the accurate classification of real and bogus transient detections in astronomical images. This network advances beyond the conventional convolutional neural network methods, widely used in image ...
A. Inada +3 more
doaj +1 more source
MathematicsTo address the low accuracy of faulty feeder detection methods based on single-fault characteristics, we propose a faulty feeder detection method for resonant grounding systems that fuses multiple transient characteristics.
Ruihao Ma, Qingle Pang
doaj +1 more source