Results 91 to 100 of about 880,701 (293)
, 2000 We study the evolution of an elastic string into the pinned state at driving forces slightly below the depinning threshold force $F_c$. We quantify the temporal evolution of the string by an {\it activity function} $A(t)$ representing the fraction of active nodes at time $t$ and find three distinct dynamic regimes.
Leaf, G. K. +3 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Numerical Simulation of Shock and Vibration Tests for Converter Cabinet
机车电传动, 2012 According to the standard GB/T 21563 2008 ’Railway applications- Rolling stock equipment- Shock and vibration tests’, the responses of the structure under random loading were computed by the finite-element analysis software ANSYS.
丁杰, 忻力, 荣智林, 陈燕平
doaj
Unravelling the Correlation of Electronic Structure and Carrier Dynamics in CuInS\u3csub\u3e2\u3c/sub\u3e Nanoparticles [PDF]
, 2017 In this work, we report the direct correlation of photoinduced carrier dynamics and electronic structure of CuInS2 (CIS) nanoparticles (NPs) using the combination of multiple spectroscopic techniques including steady-state X-ray absorption spectroscopy ...
Hu, Wenhui +7 more
core +1 more source
Symbolic dynamics of biological feedback networks
, 2009 We formulate general rules for a coarse-graining of the dynamics, which we term `symbolic dynamics', of feedback networks with monotone interactions, such as most biological modules.
Jensen, Mogens H. +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Jixie qiangdu, 2023 In view of the contact fatigue problem of the wheel side reducer gear of the drive axle of the loader during its service, the fatigue life was evaluated. Finite element models of the sun wheel and the planet wheel were established in Hypermesh.
YANG SiYuan, SONG XuDing, ZHANG Lei
doaj
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
OryxUnderstanding demographic processes is critical for conserving threatened epiphytes, yet detailed population studies remain rare. We analysed population dynamics in the context of phorophyte structure of the threatened orchid Cattleya quadricolor ...
Gabriela Torres Torres +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source