Transient Receptor Potential Channels in Prostate Cancer: Associations with ERG Fusions and Survival. [PDF]
Int J Mol SciMurugan NJ, Genautis E, Voutsadakis IA.
europepmc +1 more source
The role of transient receptor potential channels in chronic kidney disease-mineral and bone disorder. [PDF]
Front PharmacolZhang L +5 more
europepmc +1 more source
Transient receptor potential vanilloid type 4 channels mediate bladder cancer cell proliferation, migration, and chemoresistance. [PDF]
J Pharmacol Exp TherKatari V +5 more
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Corrigendum to "Functional Interaction between Transient Receptor Potential V4 Channel and Neuronal Calcium Sensor 1 and the Effects of Paclitaxel". [PDF]
Mol Pharmacoleuropepmc +1 more source
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Transient receptor potential channelopathies
Pflügers Archiv - European Journal of Physiology, 2010In the past years, several hereditary diseases caused by defects in transient receptor potential channels (TRP) genes have been described. This review summarizes our current knowledge about TRP channelopathies and their possible pathomechanisms. Based on available genetic indications, we will also describe several putative pathological conditions in ...
Bernd, Nilius, Grzegorz, Owsianik
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Transient Receptor Potential A1 Modulators
Current Topics in Medicinal Chemistry, 2011TRPA1 is a member of a superfamily of non-selective cation channels that is known to be involved in multiple physiological functions. TRPA1 is activated by a broad spectrum of chemical irritants and endogenous inflammatory compounds. An emerging role for TRPA1 in mediating pain and inflammation raises the possibility that compounds targeting TRPA1 ...
Tim, Strassmaier +1 more
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Transient Receptor Potential Channels and Mechanosensation
Annual Review of Neuroscience, 2013Transient receptor potential (TRP) channels act as sensors for a range of stimuli as diverse as light, sound, touch, pheromones, and tissue damage. Their role in mechanosensation in the animal kingdom, identified by gene ablation studies, has raised questions about whether they are directly mechanically gated, whether they act alone or in concert with ...
Niels, Eijkelkamp +2 more
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Transient Receptor Potentials (TRPs) and Anaphylaxis
Current Allergy and Asthma Reports, 2012The transient receptor potential (TRP) superfamily consists of 28 members in mammals (27 in human) that act as polymodal sensors and ion channels. They regulate cellular calcium influx, generate depolarization thereby triggering voltage dependent cellular processes, and in turn they are critical in inducing the metabolic activities of cells.
Smith, Peter K, Nilius, Bernd
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Effects of chlorpyrifos on transient receptor potential channels
Toxicology Letters, 2022The well-known toxicity of chlorpyrifos (CPF) occurs via inhibition of cholinesterase (ChE), but in recent years the detrimental effects of low-dose CPF exposure have been attributed to an unknown non-cholinergic mechanism of action. We previously showed that CPF can alter gene expression of transient receptor potential canonical (TRPC) channels in ...
Wen, Li, Marion, Ehrich
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A transient receptor potential channel expressed in taste receptor cells
Nature Neuroscience, 2002We used differential screening of cDNAs from individual taste receptor cells to identify candidate taste transduction elements in mice. Among the differentially expressed clones, one encoded Trpm5, a member of the mammalian family of transient receptor potential (TRP) channels.
Pérez, Cristian A. +7 more
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