Results 151 to 160 of about 241,409 (296)

The Landscape of Collapsar Outflows: Structure, Signatures, and Origins of Einstein Probe Relativistic Supernova Transients

open access: yesThe Astrophysical Journal Letters
The Einstein Probe is revolutionizing time-domain astrophysics through the discovery of new classes of X-ray transients associated with broad-line Type Ic supernovae.
Ore Gottlieb
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

A Luminous and Hot Infrared through X-Ray Transient at a 5 kpc Offset from a Dwarf Galaxy

open access: yesThe Astrophysical Journal
We are searching for hot, constant-color, offset optical flares in the Zwicky Transient Facility data stream that are >10″ from any galaxy in public imaging data from the PanSTARRS survey. Here, we present the first discovery from this search: AT 2024puz,
Jean J. Somalwar   +22 more
doaj   +1 more source

SFXTs as transient sources in HMXBs [PDF]

open access: yesProceedings of The Extreme and Variable High Energy Sky — PoS(Extremesky 2011), 2012
openaire   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

PEARLS: 21 Transients Found in the Three-epoch NIRCam Observations in the Continuous Viewing Zone of the James Webb Space Telescope

open access: yesThe Astrophysical Journal
We present 21 transients from our three-epoch, four-band NIRCam observations covering 14.16 arcmin ^2 in the Spitzer IRAC Dark Field (IDF), taken by the JWST Prime Extragalactic Areas for Reionization and Lensing Science program with a time cadence of ∼6
Haojing Yan   +41 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

The Impact of Accretion on FRB Radiation Mechanisms in Binary Systems: Constraints and Implications

open access: yesThe Astrophysical Journal
Fast radio bursts (FRBs) are intense, millisecond-duration radio transients that have recently been proposed to arise from coherent radiation mechanisms within the magnetosphere of neutron stars.
Gong-Yu Yao, Can-Min Deng
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Constraints on Evolutions of Fundamental Constants from Clustering of Fast Radio Burst Dispersion Measure

open access: yesThe Astrophysical Journal
Constrained measurements of fundamental physical constants using astronomical observational data represent a powerful method for investigating potential new physics. In particular, the dispersion measure (DM) of fast radio bursts (FRBs), which probes the
Shi-Yuan Wang, Jun-Qing Xia
doaj   +1 more source

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