Results 131 to 140 of about 807,144 (296)

Dinosaur in a Haystack: X-Ray View of the Entrails of SN 2023ixf and the Radio Afterglow of Its Interaction with the Medium Spawned by the Progenitor Star (Paper I)

The Astrophysical Journal
We present the results from our extensive hard-to-soft X-ray (NuSTAR, Swift-XRT, XMM-Newton, Chandra) and meter-to-millimeter-wave radio (Giant Metrewave Radio Telescope, Very Large Array, NOEMA) monitoring campaign of the very nearby ( d  = 6.9 Mpc ...
Nayana A. J., Raffaella Margutti, Eli Wiston, Ryan Chornock, Sergio Campana, Tanmoy Laskar, Kohta Murase, Melanie Krips, Giulia Migliori, Daichi Tsuna, Kate D. Alexander, Poonam Chandra, Michael Bietenholz, Edo Berger, Roger A. Chevalier, Fabio De Colle, Luc Dessart, Rebecca Diesing, Brian W. Grefenstette, Wynn V. Jacobson-Galán, Keiichi Maeda, Benito Marcote, Daisy Matthews, Dan Milisavljevic, Alak K. Ray, Andrea Reguitti, Ava Polzin   +26 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Delayed Radio Emission in Tidal Disruption Events from Collisions of Outflows Driven by Disk Instabilities

The Astrophysical Journal
Delayed radio emission has been associated with a growing proportion of tidal disruption events (TDEs). For many events, the radio synchrotron emission is inferred to originate from the interaction of mildly relativistic outflows, launched with delay ...
Samantha C. Wu, Daichi Tsuna, Brenna Mockler, Anthony L. Piro   +3 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Eddington Envelopes: The Fate of Stars on Parabolic Orbits Tidally Disrupted by Supermassive Black Holes

The Astrophysical Journal Letters
Stars falling too close to massive black holes in the centers of galaxies can be torn apart by the strong tidal forces. Simulating the subsequent feeding of the black hole with disrupted material has proved challenging because of the range of timescales ...
Daniel J. Price, David Liptai, Ilya Mandel, Joanna Shepherd, Giuseppe Lodato, Yuri Levin   +5 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

The Landscape of Collapsar Outflows: Structure, Signatures, and Origins of Einstein Probe Relativistic Supernova Transients

The Astrophysical Journal Letters
The Einstein Probe is revolutionizing time-domain astrophysics through the discovery of new classes of X-ray transients associated with broad-line Type Ic supernovae.
Ore Gottlieb
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A Luminous and Hot Infrared through X-Ray Transient at a 5 kpc Offset from a Dwarf Galaxy

The Astrophysical Journal
We are searching for hot, constant-color, offset optical flares in the Zwicky Transient Facility data stream that are >10″ from any galaxy in public imaging data from the PanSTARRS survey. Here, we present the first discovery from this search: AT 2024puz,
Jean J. Somalwar, Vikram Ravi, Raffaella Margutti, Ryan Chornock, Priyamvada Natarajan, Wenbin Lu, Charlotte Angus, Matthew J. Graham, Erica Hammerstein, Edward Nathan, Matt Nicholl, Kritti Sharma, Robert Stein, Frank Verdi, Yuhan Yao, Eric C. Bellm, Tracy X. Chen, Michael W. Coughlin, David Hale, Mansi M. Kasliwal, Russ R. Laher, Reed Riddle, Jesper Sollerman   +22 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source