Results 121 to 130 of about 807,144 (296)

A Catalog of Local Universe Fast Radio Bursts from CHIME/FRB and the KKO

The Astrophysical Journal Supplement Series
We present the first catalog of fast radio burst (FRB) host galaxies from CHIME/FRB Outriggers, selected uniformly in the radio and the optical by localizing 81 new bursts to 2″ × ∼ 60″ accuracy using CHIME and the k’niʔatn k’l ⌣ stk’masqt Outrigger ...
The CHIME/FRB Collaboration, Mandana Amiri, Daniel Amouyal, Bridget C. Andersen, Shion Andrew, Kevin Bandura, Mohit Bhardwaj, P. J. Boyle, Charanjot Brar, Alyssa Cassity, Shami Chatterjee, Alice P. Curtin, Matt Dobbs, Fengqiu Adam Dong, Yuxin Dong, Gwendolyn M. Eadie, Tarraneh Eftekhari, Wen-fai Fong, Emmanuel Fonseca, B. M. Gaensler, Mark Halpern, Jason W. T. Hessels, Hans Hopkins, Adaeze L. Ibik, Ronniy C. Joseph, Jane Kaczmarek, Lordrick Kahinga, Victoria Kaspi, Kholoud Khairy, Charles D. Kilpatrick, Adam E. Lanman, Mattias Lazda, Calvin Leung, Robert Main, Lluis Mas-Ribas, Kiyoshi W. Masui, Ryan Mckinven, Juan Mena-Parra, Bradley W. Meyers, Daniele Michilli, Nikola Milutinovic, Kenzie Nimmo, Gavin Noble, Ayush Pandhi, Swarali Shivraj Patil, Aaron B. Pearlman, Emily Petroff, Ziggy Pleunis, J. Xavier Prochaska, Masoud Rafiei-Ravandi, Mubdi Rahman, Andre Renard, Mawson W. Sammons, Ketan R. Sand, Paul Scholz, Vishwangi Shah, Kaitlyn Shin, Seth R. Siegel, Sunil Simha, Kendrick Smith, Ingrid Stairs, Keith Vanderlinde, Haochen Wang, Dallas Wulf, Tarik J. Zegmott   +64 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Sudden Polarization Angle Jumps of the Repeating Fast Radio Burst FRB 20201124A

The Astrophysical Journal Letters
We report the first detection of polarization angle orthogonal jumps, a phenomenon previously only observed from radio pulsars, from a fast radio burst (FRB) source FRB 20201124A.
J. R. Niu, W. Y. Wang, J. C. Jiang, Y. Qu, D. J. Zhou, W. W. Zhu, K. J. Lee, J. L. Han, B. Zhang, D. Li, S. Cao, Z. Y. Fang, Y. Feng, Q. Y. Fu, P. Jiang, W. C. Jing, J. Li, Y. Li, R. Luo, L. Q. Meng, C. C. Miao, X. L. Miao, C. H. Niu, Y. C. Pan, B. J. Wang, F. Y. Wang, H. Z. Wang, P. Wang, Q. Wu, Z. W. Wu, H. Xu, J. W. Xu, L. Xu, M. Y. Xue, Y. P. Yang, M. Yuan, Y. L. Yue, D. Zhao, C. F. Zhang, D. D. Zhang, J. S. Zhang, S. B. Zhang, Y. K. Zhang, Y. H. Zhu   +43 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Transient difference solutions of the inhomogeneous wave equation: Simulation of the Green's function [PDF]

A time-dependent finite difference formulation to the inhomogeneous wave equation is derived for plane wave propagation with harmonic noise sources. The difference equation and boundary conditions are developed along with the techniques to simulate the ...
Baumeiste, K. J.
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Synchrotron Break Frequencies of Mildly to Highly Relativistic Outflows Observed Off-axis

The Astrophysical Journal
We consider the synchrotron spectrum produced by mildly to highly relativistic collisionless shocks. Simple analytic formulae are derived for the break frequencies (peak frequency, self-absorption frequency, synchrotron, and inverse Compton cooling ...
Gilad Sadeh
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Searching for Historical Extragalactic Optical Transients Associated with Fast Radio Bursts

The Astrophysical Journal
We present a systematic search for past supernovae (SNe) and other historical optical transients at the positions of fast radio burst (FRB) sources to test FRB progenitor systems.
Y. Dong, C. D. Kilpatrick, W. Fong, A. P. Curtin, S. Opoku, B. C. Andersen, A. M. Cook, T. Eftekhari, E. Fonseca, B. M. Gaensler, R. C. Joseph, J. F. Kaczmarek, L. A. Kahinga, V. Kaspi, A. E. Lanman, M. Lazda, C. Leung, K. W. Masui, D. Michilli, K. Nimmo, A. Pandhi, A. B. Pearlman, M. Sammons, P. Scholz, V. Shah, K. Shin, K. Smith   +26 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source