Results 31 to 40 of about 4,124,580 (330)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Target Search for Fast Radio Bursts Associated with Two Fast Blue Optical Transients: AT2018cow and CSS161010

The Astrophysical Journal
Fast blue optical transients (FBOTs) are luminous, rapidly evolving events with blue spectra, possibly powered by newborn magnetars and linked to fast radio bursts (FRBs).
Shi-Jie Gao, Xiang-Dong Li, Yi-Xuan Shao, Ping Zhou, Pei Wang, Yun-Wei Yu, Zhen Yan, Di Li   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Radio Flare and Multiwavelength Afterglow of the Short GRB 231117A: Energy Injection from a Violent Shell Collision

The Astrophysical Journal
We present the early radio detection and multiwavelength modeling of the short gamma-ray burst (GRB) 231117A at redshift z = 0.257. The Australia Telescope Compact Array automatically triggered a 9 hr observation of GRB 231117A at 5.5 and 9 GHz following
G. E. Anderson, G. P. Lamb, B. P. Gompertz, L. Rhodes, A. Martin-Carrillo, A. J. van der Horst, A. Rowlinson, M. E. Bell, T.-W. Chen, H. M. Fausey, M. Ferro, P. J. Hancock, S. R. Oates, S. Schulze, R. L. C. Starling, S. Yang, K. Ackley, J. P. Anderson, A. Andersson, J. F. Agüí Fernández, R. Brivio, E. Burns, K. C. Chambers, T. de Boer, V. D’Elia, M. De Pasquale, A. de Ugarte Postigo, Dimple, R. Fender, M. D. Fulton, H. Gao, J. H. Gillanders, D. A. Green, M. Gromadzki, A. Gulati, D. H. Hartmann, M. E. Huber, N. J. Klingler, N. P. M. Kuin, J. K. Leung, A. J. Levan, C.-C. Lin, E. Magnier, D. B. Malesani, P. Minguez, K. P. Mooley, T. Mukherjee, M. Nicholl, P. T. O’Brien, G. Pugliese, A. Rossi, S. D. Ryder, B. Sbarufatti, B. Schneider, F. Schüssler, S. J. Smartt, K. W. Smith, S. Srivastav, D. Steeghs, N. R. Tanvir, C. C. Thoene, S. D. Vergani, R. J. Wainscoat, Z.-N. Wang, R. A. M. J. Wijers, D. Williams-Baldwin, I. Worssam, T. Zafar   +67 more
doaj   +1 more source

Subarcminute Localization of 13 Repeating Fast Radio Bursts Detected by CHIME/FRB

The Astrophysical Journal, 2023
We report on improved sky localizations of 13 repeating fast radio bursts (FRBs) discovered by CHIME/FRB via the use of interferometric techniques on channelized voltages from the telescope.
Daniele Michilli, Mohit Bhardwaj, Charanjot Brar, B. M. Gaensler, Victoria M. Kaspi, Aida Kirichenko, Kiyoshi W. Masui, Ryan Mckinven, Cherry Ng, Chitrang Patel, Ketan R. Sand, Paul Scholz, Kaitlyn Shin, Seth R. Siegel, Ingrid Stairs, Tomas Cassanelli, Amanda M. Cook, Matt Dobbs, Fengqiu Adam Dong, Emmanuel Fonseca, Adaeze Ibik, Jane Kaczmarek, Calvin Leung, Aaron B. Pearlman, Emily Petroff, Ziggy Pleunis, Masoud Rafiei-Ravandi, Pranav Sanghavi, J. Richard Shaw, Shriharsh P. Tendulkar   +29 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Photohadronic neutrinos from transients in astrophysical sources

Physical Review D, 1998
Significant corrections and changes in presentation, no changes in the result. Symbol table added.
Rachen, Jorg P., Meszaros, P.
openaire   +2 more sources

Continued Radio Observations of the Persistent Radio Source Associated with FRB 20190520B Provide Insights into Its Origin

The Astrophysical Journal
Follow-up studies of persistent emission from fast radio burst (FRB) sources are critical for understanding their elusive emission mechanisms and the nature of their progenitors.
Arvind Balasubramanian, Mohit Bhardwaj, Shriharsh P. Tendulkar   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source