Results 51 to 60 of about 4,124,580 (330)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
We present a search for bright, transient emission lines near 0.5 MeV in nearly two years of data from the Burst and Transient Source Experiment (BATSE) on the Compton Gamma-Ray Observatory, Such features have been reported from black hole candidates Nova Muscae and 1E 1740.7-2942 and from the Crab, lasting for about 1 day.
D. M. Smith +5 more
openaire +1 more source
The First Photometric Evidence of a Transient/Variable Source at z > 5 with JWST
The James Webb Space Telescope (JWST) discovered 79 transients out to z ∼ 4.8 through the JADES Transient Survey (JTS), but the JTS did not find any z > 5 transients.
Christa DeCoursey +29 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Eight Years of Light from ASASSN-15oi: Toward Understanding the Late-time Evolution of TDEs
We present results from an extensive follow-up campaign of the tidal disruption event (TDE) ASASSN-15oi spanning δt ∼ 10–3000 days, offering an unprecedented window into the multiwavelength properties of a TDE during its first ≈8 yr of evolution. ASASSN-
A. Hajela +28 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The Effect of the Velocity Distribution on Kilonova Emission
The electromagnetic emission from the nonrelativistic ejecta launched in neutron star mergers (either dynamically or through a disk wind) has the potential to probe both the total mass and composition of this ejecta.
Chris L. Fryer +9 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core
Transient application card documenting relief requests and authorizations to the destitute by Transient Bureau of Kalamazoo County, under the Federal Emergency Relief Administration, May 1933 - June ...
Kalamazoo County (Mich.). Transient Bureau
core +1 more source

