Results 51 to 60 of about 227,458 (266)

Eight Years of Light from ASASSN-15oi: Toward Understanding the Late-time Evolution of TDEs

open access: yesThe Astrophysical Journal
We present results from an extensive follow-up campaign of the tidal disruption event (TDE) ASASSN-15oi spanning δt  ∼ 10–3000 days, offering an unprecedented window into the multiwavelength properties of a TDE during its first ≈8 yr of evolution. ASASSN-
A. Hajela   +28 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The Effect of the Velocity Distribution on Kilonova Emission

open access: yesThe Astrophysical Journal
The electromagnetic emission from the nonrelativistic ejecta launched in neutron star mergers (either dynamically or through a disk wind) has the potential to probe both the total mass and composition of this ejecta.
Chris L. Fryer   +9 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Multiwavelength Analysis of Six Luminous Fast Blue Optical Transients

open access: yesThe Astrophysical Journal
We present early (≲1 yr) multiwavelength observations and analysis of six luminous fast blue optical transients (LFBOTs). We identified these LFBOTs in Zwicky Transient Facility survey data from their fast light-curve evolution ( t _1/2 ≤ 12 days), blue ...
Cassie Sevilla   +45 more
doaj   +1 more source

Recent Transient X-Ray Sources [PDF]

open access: yesHighlights of Astronomy, 1977
Prior to the launch of the Ariel V satellite in 1974, four transient X-ray sources had been observed. We placed the study of sources of this type amongst the major objectives of the satellite, and so ensured that the spacecraft ground centre was capable of quick reaction, and that experimenters had rapid access to their data, so that new transients ...
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Radio Counterpart to the Fast X-Ray Transient EP240414a

open access: yesThe Astrophysical Journal
Despite being operational for only a short time, the Einstein Probe mission, with its large field of view and rapid localization capabilities, has already significantly advanced the study of rapid variability in the soft X-ray sky.
Joe S. Bright   +12 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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