Results 41 to 50 of about 4,124,580 (330)
Optical Appearance of Eccentric Tidal Disruption Events
The Astrophysical Journal LettersStars approaching supermassive black holes can be tidally disrupted. Despite being expected to emit X-rays, tidal disruption events (TDEs) have been largely observed in optical bands, which is poorly understood.
Fangyi (Fitz) Hu +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Late-time Radio Flares in Tidal Disruption Events
The Astrophysical JournalRadio monitoring unveiled late (hundreds to a thousand days) radio flares in a significant fraction of tidal disruption events. We propose that these late-time radio flares are a natural outcome if the surrounding density profile flattens outside the ...
Tatsuya Matsumoto, Tsvi Piran
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Possible Periodic Rotation Measure Evolution in the Repeating FRB 20220529
The Astrophysical Journal LettersFast radio bursts (FRBs) are mysterious millisecond-duration radio transients of extragalactic origin. Some of them repeat, while others apparently do not.
Yi-Fang Liang +20 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Multiwavelength Observations of the Apparently Nonrepeating FRB 20250316A
The Astrophysical JournalThe physical origin of fast radio bursts (FRBs) remains uncertain. Although multiwavelength observations have been widely conducted, only Galactic FRB 20200428D is associated with an X-ray burst from the magnetar SGR J1935+2154.
Ye Li +74 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Massive and Quiescent Elliptical Host Galaxy of the Repeating Fast Radio Burst FRB 20240209A
The Astrophysical Journal LettersThe discovery and localization of FRB 20240209A by the Canadian Hydrogen Intensity Mapping Fast Radio Burst (CHIME/FRB) experiment marks the first repeating FRB localized with the CHIME/FRB Outriggers and adds to the small sample of repeating FRBs with ...
T. Eftekhari +41 more
doaj +1 more source