Results 41 to 50 of about 227,458 (266)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A Possible Periodic Rotation Measure Evolution in the Repeating FRB 20220529
The Astrophysical Journal LettersFast radio bursts (FRBs) are mysterious millisecond-duration radio transients of extragalactic origin. Some of them repeat, while others apparently do not.
Yi-Fang Liang +20 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Multiwavelength Observations of the Apparently Nonrepeating FRB 20250316A
The Astrophysical JournalThe physical origin of fast radio bursts (FRBs) remains uncertain. Although multiwavelength observations have been widely conducted, only Galactic FRB 20200428D is associated with an X-ray burst from the magnetar SGR J1935+2154.
Ye Li +74 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Massive and Quiescent Elliptical Host Galaxy of the Repeating Fast Radio Burst FRB 20240209A
The Astrophysical Journal LettersThe discovery and localization of FRB 20240209A by the Canadian Hydrogen Intensity Mapping Fast Radio Burst (CHIME/FRB) experiment marks the first repeating FRB localized with the CHIME/FRB Outriggers and adds to the small sample of repeating FRBs with ...
T. Eftekhari +41 more
doaj +1 more source
The Astrophysical Journal, 1996 We present a search for bright, transient emission lines near 0.5 MeV in nearly two years of data from the Burst and Transient Source Experiment (BATSE) on the Compton Gamma-Ray Observatory, Such features have been reported from black hole candidates Nova Muscae and 1E 1740.7-2942 and from the Crab, lasting for about 1 day.
D. M. Smith +5 more
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The First Photometric Evidence of a Transient/Variable Source at z > 5 with JWST
The Astrophysical JournalThe James Webb Space Telescope (JWST) discovered 79 transients out to z ∼ 4.8 through the JADES Transient Survey (JTS), but the JTS did not find any z > 5 transients.
Christa DeCoursey +29 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source