Results 71 to 80 of about 807,144 (296)

Eight Years of Light from ASASSN-15oi: Toward Understanding the Late-time Evolution of TDEs

open access: yesThe Astrophysical Journal
We present results from an extensive follow-up campaign of the tidal disruption event (TDE) ASASSN-15oi spanning δt  ∼ 10–3000 days, offering an unprecedented window into the multiwavelength properties of a TDE during its first ≈8 yr of evolution. ASASSN-
A. Hajela   +28 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Effect of the Velocity Distribution on Kilonova Emission

open access: yesThe Astrophysical Journal
The electromagnetic emission from the nonrelativistic ejecta launched in neutron star mergers (either dynamically or through a disk wind) has the potential to probe both the total mass and composition of this ejecta.
Chris L. Fryer   +9 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Radio Counterpart to the Fast X-Ray Transient EP240414a

open access: yesThe Astrophysical Journal
Despite being operational for only a short time, the Einstein Probe mission, with its large field of view and rapid localization capabilities, has already significantly advanced the study of rapid variability in the soft X-ray sky.
Joe S. Bright   +12 more
doaj   +1 more source

Swift follow-up of unidentified X-ray sources in the XMM-Newton Slew Survey

open access: yes, 2010
We present deep Swift follow-up observations of a sample of 94 unidentified X-ray sources from the XMM-Newton Slew Survey. The X-ray Telescope on-board Swift detected 29% of the sample sources; the flux limits for undetected sources suggests the bulk of ...
A. M. Read   +64 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The Nature of Optical Afterglows without Gamma-Ray Bursts: Identification of AT2023lcr and Multiwavelength Modeling

open access: yesThe Astrophysical Journal
In the past few years, the improved sensitivity and cadence of wide-field optical surveys have enabled the discovery of several afterglows without associated detected gamma-ray bursts (GRBs).
Maggie L. Li   +31 more
doaj   +1 more source

IMPLEMENTATION OF THE COMBINED RELAY PROTECTION SYSTEMS IN DISTRIBUTION GRIDS WITH SEVERAL SOURCES [PDF]

open access: yes, 2018
Creation and integration of relay protection combined structures based on microelectronic and electromechanical elements into distributed electric networks for costs reducing and improvement of their operation modes reliability ...
KOSHELENKO, Ievgenii   +3 more
core  

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