Results 71 to 80 of about 227,458 (266)

Bright Bursts with Submillisecond Structures of FRB 20230607A in a Highly Magnetized Environment

open access: yesThe Astrophysical Journal
We report the observations of a repeating FRB 20230607A for 15.6 hr spanning 16 months using the Five-hundred-meter Aperture Spherical Radio Telescope with the detection of 565 bursts.
DeJiang Zhou   +21 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

CSS 161010: A Luminous Fast Blue Optical Transient with Broad Blueshifted Hydrogen Lines

open access: yesThe Astrophysical Journal
We present ultraviolet, optical, and near-infrared photometric and optical spectroscopic observations of the luminous fast blue optical transient (LFBOT) CSS 161010:045834–081803 (CSS 161010).
Claudia P. Gutiérrez   +40 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Transient sources at the highest angular resolution [PDF]

open access: yesProceedings of 12th European VLBI Network Symposium and Users Meeting — PoS(EVN 2014), 2015
By definition transients are sudden events, some, like supernovae, are catastrophic, while others might be due to recurrent phenomena. The aim of studying transients is to reveal the physical conditions causing them, in this sense ideal targets for monitoring are transients in binary systems.
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

An Extremely Active Repeating Fast Radio Burst Source in a Likely Nonmagneto-ionic Environment

open access: yesThe Astrophysical Journal
Fast radio bursts (FRBs) are bright radio bursts originating at cosmological distances. Only three repeating FRBs FRB 20121102A, FRB 20190520B, and FRB 20201124A among ∼60 known repeating FRBs have circular polarization.
Yi Feng   +27 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Radio Observations Point to a Moderately Relativistic Outflow in the Fast X-Ray Transient EP241021a

open access: yesThe Astrophysical Journal
Fast X-ray transients (FXRTs) are short-lived X-ray outbursts with diverse progenitor scenarios, including compact object mergers, stellar core collapses, and tidal disruption events.
Muskan Yadav   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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