Results 91 to 100 of about 807,144 (296)

Follow-up of X-ray transients detected by SWIFT with COLORES using the BOOTES network

open access: yes, 2015
The Burst Observer and Optical Transient Exploring System (BOOTES) is a network of telescopes that allows the continuous monitoring of transient astrophysical sources.
Caballero-Garcia, M. D.   +6 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Bright Bursts with Submillisecond Structures of FRB 20230607A in a Highly Magnetized Environment

open access: yesThe Astrophysical Journal
We report the observations of a repeating FRB 20230607A for 15.6 hr spanning 16 months using the Five-hundred-meter Aperture Spherical Radio Telescope with the detection of 565 bursts.
DeJiang Zhou   +21 more
doaj   +1 more source

The Chandra ACIS Survey of M33 (ChASeM33): Transient X-ray Sources Discovered in M33

open access: yes, 2008
The Chandra ACIS Survey of M33 (ChASeM33) has acquired 7 fields of ACIS data covering M33 with 200 ks of exposure in each field. A catalog from the first 10 months of data, along with archival Chandra observations dating back to the year 2000, is ...
Avi Shporer   +14 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CSS 161010: A Luminous Fast Blue Optical Transient with Broad Blueshifted Hydrogen Lines

open access: yesThe Astrophysical Journal
We present ultraviolet, optical, and near-infrared photometric and optical spectroscopic observations of the luminous fast blue optical transient (LFBOT) CSS 161010:045834–081803 (CSS 161010).
Claudia P. Gutiérrez   +40 more
doaj   +1 more source

Swift J1644+57: An Ultra-Luminous X-ray Event

open access: yes, 2012
The photon spectral energy distribution of the powerful transient Sw J1644+57 resembles those of the brightest Ultra-Luminous X-ray sources (ULXs).
Goodman   +13 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

An Extremely Active Repeating Fast Radio Burst Source in a Likely Nonmagneto-ionic Environment

open access: yesThe Astrophysical Journal
Fast radio bursts (FRBs) are bright radio bursts originating at cosmological distances. Only three repeating FRBs FRB 20121102A, FRB 20190520B, and FRB 20201124A among ∼60 known repeating FRBs have circular polarization.
Yi Feng   +27 more
doaj   +1 more source

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