Results 131 to 140 of about 826,407 (343)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Transient Frequency Modeling and Characteristic Analysis of Virtual Synchronous Generator

open access: yesEnergies
The large-scale integration of renewable energy into power systems significantly alters their operational characteristics, reducing system inertia and posing challenges to transient frequency stability.
Zhou Su, Guoqing Yang, Lixiao Yao
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Study on Transient Stability of Circulation Economy Power System with High Penetration of Wind Power

open access: hybrid, 2014
Jianping Liu   +5 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An optimal allocation strategy for GFM and GFL converters considering transient voltage stability constraints

open access: yesZhejiang dianli
The hybrid grid-forming (GFM) and grid-following (GFL) converter integration systems combine the technical advantages of GFM voltage sources and GFL current sources.
LI Qun   +3 more
doaj   +1 more source

Transient Stability Assessment of Cascade Tripping of Renewable Sources Using SOS [PDF]

open access: green, 2018
Chetan Mishra   +3 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Transient Stability Enhancement in Microgrids:

open access: yesSolar Energy and Sustainable Development Journal
The widespread integration of renewable energy sources, such as photovoltaic (PV) and wind power, poses significant challenges to power system stability. This study investigates the combined effect of a Power System Stabilizer (PSS) and a Static Var Compensator (SVC) in enhancing transient stability during sequential symmetrical and asymmetrical faults.
Siradj Younes   +2 more
openaire   +1 more source

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