Results 61 to 70 of about 71,034 (269)

A unified viscoelastic-viscoplastic constitutive framework for optically clear adhesives: Experiments, modeling, and FE validation

open access: yesMicrosystems & Nanoengineering
Optically clear adhesives (OCAs) are extensively employed as bonding layers in display manufacturing. As compliant interlayers in foldable display stacks, they undergo pronounced time and temperature -dependent deformation during repeated bending, which ...
Zhaoxu Zhou   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Research of controlled switching strategy to restrain inrush current during the energisation of converter transformer

open access: yesThe Journal of Engineering, 2019
When an unloaded converter transformer is being energised, large inrush current may flow in the voltage jump side depending upon the residual flux in the core and the closing voltage angle of the power grid due to the hysteresis characteristics of the ...
Duo Wang   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Noise-induced stabilization of saddle-node ghosts

open access: yesNew Journal of Physics, 2020
It is known that saddle-node (s-n) bifurcations leave a saddle remnant (or ghost) in the region of the phase space where the annihilation of the fixed points occurred.
Josep Sardanyés   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Compton scattering X-ray imaging system for material detection through 3 mm aluminum shielding for potential future space application

open access: yesPhysics Letters B
This paper explores the application of Compton scattering imaging for the active detection of space debris at long distances and through dense metallic shielding.
Yun Li   +9 more
doaj   +1 more source

Transient congenital hypothyroidism – too short to be transient

open access: yesJournal of Postgraduate Medicine, 2021
Congenital hypothyroidism (CH) occurs due to thyroid dysgenesis, thyroid ectopy, and dyshormonogenesis. A proportion of CH is transient which might be due to iodine deficiency/excess or maternal antibody-mediated. Certain forms of dyshormonogenetic defects may cause transient hypothyroidism.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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