Results 71 to 80 of about 70,580 (269)

Compton scattering X-ray imaging system for material detection through 3 mm aluminum shielding for potential future space application

open access: yesPhysics Letters B
This paper explores the application of Compton scattering imaging for the active detection of space debris at long distances and through dense metallic shielding.
Yun Li   +9 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Influence of sinusoidal and square voltages on partial discharge inception in geometries with point-like termination

open access: yesHigh Voltage, 2018
High-voltage equipment involves both electrical and electronic components. In electrical power network, which consists of rotating machine, power transformers and transmission lines, field enhancement at critical regions can lead to local breakdown ...
Abdelghaffar A. Abdelmalik
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Transient Faults in Wind Energy Conversion Systems: Analysis, Modelling Methodologies and Remedies

open access: yesEnergies, 2018
This paper presents an in-depth review of classical and state-of-the-art models for analysing the transient stability in wind energy conversion systems.
Ukashatu Abubakar   +7 more
doaj   +1 more source

The Transient Predictor

open access: yes2024 IEEE 63rd Conference on Decision and Control (CDC)
This paper introduces the Transient Predictor and describes how it can be used to estimate the Multistep Predictor, which can be applied to applications such as Data-Driven Predictive Control (DDPC). The Transient Predictor has two desirable traits that differentiate it from other methods for estimating the Multistep Predictor, such as the standard ...
Moffat, Keith   +2 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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