Results 81 to 90 of about 71,034 (269)

Vibration Analysis of Al–Al2O3 Micro-Cantilever Sandwich Beams with Porosity in Fluids

open access: yesMicromachines
The vibration of porous Al–Al2O3 micro-cantilever sandwich beams in fluids was studied utilizing the modified couple stress theory and the scale distribution theory (MCST and SDT).
Feixiang Tang   +9 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Performance Assessment of Pneumatic-Driven Automatic Valves to Improve Pipeline Fault Detection Procedure by Fast Transient Tests

open access: yesSensors
The use of fast transients for fault detection in long transmission networks makes the generation of controlled transients crucial. In order to maximise the information that can be extracted from the measured pressure time history (pressure signal), the ...
Francesco Castellani   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Correlation between the solar wind speed and the passage of poleward-moving auroral forms into the polar cap

open access: yesFrontiers in Astronomy and Space Sciences
In 1961, Dungey suggested that magnetic reconnection occurs due to the solar-terrestrial interaction. The interplanetary magnetic field (IMF) is thought to merge with Earth’s geomagnetic field (GMF).
G. J. Fasel   +10 more
doaj   +1 more source

A transient frenzy?

open access: yesBMJ, 1998
“Deadly Secrets”, a QED documentary on 5 August examines the issue of neonaticide. Gwen Adshead says there is still some way to go in understanding the motivations behind this human tragedy.      In 1902 Dr John Baker, a physician superintendent of Broadmoor Hospital, had this to say about women who kill their newborn children: “This class of crime ...
openaire   +3 more sources

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