Results 121 to 130 of about 133,301 (317)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Analysis on Computer Interlocking Logic Design for Main Line of Urban Rail Transit
机车电传动, 2012 Function of computer interlocking equipment, which was considered as one of core subsystem of signal system was discussed. Moreover, in terms of practical requirement, a modified method of interlocking logic realization was proposed.
LIANG Yun-peng, WANG Cheng, LV Hao-jiong
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modeling a rail transit alignment considering different objectives [PDF]
, 2010 An optimization model for station locations for an on-ground rail transit line is developed using different objective functions of demand and cost as both influence the planning of a rail transit alignment.
Sutapa Samanta +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Transit and Trade Barriers in Eastern South Asia: A Review of the Transit Regime and Performance of Strategic Border-Crossings [PDF]
The analysis of this paper shows that a regional transit arrangement would perhaps enhance the regional trade, controlling for other variables. At the same time, implementation of e-governance at border is found to be significant determinant of trade ...
Sachin Chaturvedi +2 more
core
The Atlanta Beltline: Transit Feasibility White Paper [PDF]
, 2005 The BeltLine Transit Panel was assembled by the Atlanta Development Authority (ADA) to review the studies done to date on the BeltLine project and assess and comment on the feasibility of the transit component and how it might function in relation to an
Millar, William W. +4 more
core
2-Vehicle zone optimal design for feeder transit services [PDF]
, 2011 Feeder transit services perform the crucial first/last mile access to transit by connecting people within a residential area to a major transit network.
Quadrifoglio, Luca +3 more
core +1 more source
A Systematic Review of the Coopetition Relationship between Bike-Sharing and Public Transit
Journal of Advanced TransportationThe sharing economy, mobile Internet, and smartphones have been widely utilized in recent years to promote the development of bike-sharing services. Bike-sharing serves as a first/last mile travel mode to connect to public transit, which improves trip ...
Jianhong Ye, Jiahao Bai, WenYang Hao
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source