Results 121 to 130 of about 75,518 (268)

Tidally Heated Sub-Neptunes, Refined Planetary Compositions, and Confirmation of a Third Planet in the TOI-1266 System

open access: yesThe Astronomical Journal
TOI-1266 is a benchmark system of two temperate (
Michael Greklek-McKeon   +40 more
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao   +7 more
wiley   +1 more source

A Compact Multiplanet System of Three Transiting Giant Planets around TIC 118798035

open access: yesThe Astrophysical Journal Letters
We report the discovery and characterization of three transiting giant planets in the TIC 118798035 system. The three planets were identified as transiting candidates from data of the TESS mission and confirmed with ground-based photometric transit ...
Rafael Brahm   +22 more
doaj   +1 more source

Real-time Evaluation Model for Metro Station Passenger Flow Streamline Congestion State

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Implementing precise initiation, performance evaluation and dynamic information dissemination of metro station large passenger flow management and control measures requires more effective support.
SHI Pingcui   +4 more
doaj   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

TrES-1 b: A Case Study in Detecting Secular Evolution of Exoplanet Orbits

open access: yesThe Astronomical Journal
We present a comprehensive analysis of transit, eclipse, and radial velocity data of the hot Jupiter TrES-1 b and confirm evidence of orbital variations on secular timescales.
Simone R. Hagey   +45 more
doaj   +1 more source

Transit Timing Analysis in the HAT-P-32 System

open access: yes, 2014
We present the results of 45 transit observations obtained for the transiting exoplanet HATP- 32b. The transits have been observed using several telescopes mainly throughout the YETI (Young Exoplanet Transit Initiative) network.
Ak, T.   +26 more
core  

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

The Exoplanet Edge: Planets Do Not Induce Observable Transit Timing Variations with a Dominant Transit Timing Variation Period Faster than Half Their Orbital Period

open access: yesThe Astrophysical Journal Letters
Transit timing variations (TTVs) are observed for exoplanets at a range of amplitudes and periods, yielding an ostensibly degenerate forest of possible explanations.
Daniel A. Yahalomi   +3 more
doaj   +1 more source

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