Results 131 to 140 of about 13,276,104 (255)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

In Search of Decay: An Analysis of Transit Times of Hot Jupiters in Main-sequence and Post-main-sequence Systems

The Astrophysical Journal
Tidal interactions are one of the primary drivers of orbital evolution for massive planets with short orbital periods. Tidal dissipation within host stars can cause the orbits of such planets to decay.
Noah Sodickson, Samuel Grunblatt
doaj   +1 more source

How time-inconsistent preferences affect investment timing for rail transit

, 2018
We address optimal rail transit investment issues considering time-inconsistent preferences and population uncertainty. Instead of adopting the typical real options approach which assumes that authorities possess a constant discount rate over time, we ...
Li, Zhongfei, Chen, Shumin, Schonfeld, Paul, Guo, Qian-Wen   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Orbital Decay of the Ultra-hot Jupiter TOI-2109b: Tidal Constraints and Transit-timing Analysis

The Astrophysical Journal
TOI-2109b is the ultra-hot Jupiter with the shortest orbital period (∼16 hr) yet discovered. At this close distance, strong tidal interactions can produce a significant exchange of angular momentum with the star.
Jaime A. Alvarado-Montes, Mario Sucerquia, Jorge I. Zuluaga, Christian Schwab   +3 more
doaj   +1 more source

Oregon Department of Transportation Public Transit [organization chart]

, 2008
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Aug.

core  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The TESS-Keck Survey. XVII. Precise Mass Measurements in a Young, High-multiplicity Transiting Planet System Using Radial Velocities and Transit Timing Variations

The Astronomical Journal
We present a radial velocity (RV) analysis of TOI-1136, a bright Transiting Exoplanet Survey Satellite (TESS) system with six confirmed transiting planets, and a seventh single-transiting planet candidate.
Corey Beard, Paul Robertson, Fei Dai, Rae Holcomb, Jack Lubin, Joseph M. Akana Murphy, Natalie M. Batalha, Sarah Blunt, Ian Crossfield, Courtney Dressing, Benjamin Fulton, Andrew W. Howard, Dan Huber, Howard Isaacson, Stephen R. Kane, Grzegorz Nowak, Erik A Petigura, Arpita Roy, Ryan A. Rubenzahl, Lauren M. Weiss, Rafael Barrena, Aida Behmard, Casey L. Brinkman, Ilaria Carleo, Ashley Chontos, Paul A. Dalba, Tara Fetherolf, Steven Giacalone, Michelle L. Hill, Kiyoe Kawauchi, Judith Korth, Rafael Luque, Mason G. MacDougall, Andrew W. Mayo, Teo Močnik, Giuseppe Morello, Felipe Murgas, Jaume Orell-Miquel, Enric Palle, Alex S. Polanski, Malena Rice, Nicholas Scarsdale, Dakotah Tyler, Judah Van Zandt   +43 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Mapping the Orbital Landscape of Perturbing Planet Solutions for Single-planet Systems with TTVs

The Astrophysical Journal
There are now thousands of single-planet systems observed to exhibit transit timing variations (TTVs), yet we largely lack any interpretation of the implied masses responsible for these perturbations.
Daniel A. Yahalomi, David Kipping
doaj   +1 more source