Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A Study of R-R Interval Transition Matrix Features for Machine Learning Algorithms in AFib Detection. [PDF]
Sensors (Basel), 2023 Patel S, Wang M, Guo J, Smith G, Chen C.
europepmc +1 more source
, 2012 The soil aggregate stability is a key property of soil quality and reflects soil quality and anti-erosion ability. The transition matrix between initial and final aggregates condition was established by modifying Niewczas and Witkowska-Walczak's method ...
Shao, Hong-Bo, Shi, Hui
core
Appendix C. Mean microhabitat transition matrix, Cij.
, 2016 Mean microhabitat transition matrix ...
Warren Y. Brockelman (2916815) +3 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Delineating the Intrinsic, Long-Term Path of Land Degradation: A Spatially Explicit Transition Matrix for Italy, 1960-2010. [PDF]
Int J Environ Res Public Health, 2023 Pace L +6 more
europepmc +1 more source
On matrix model partition functions for QCD with chemical potential
, 2004 Partition functions of two different matrix models for QCD with chemical potential are computed for an arbitrary number of quark and complex conjugate anti-quark flavors. In the large-N limit of weak nonhermiticity complete agreement is found between the
Akemann, G +5 more
core +1 more source
Transition matrix showing how many times each transition was used during the trial period.
, 2022 Transition matrix showing how many times each transition was used during the trial period.
Zafar Malik (12733728) +21 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Influence of different playing styles among the top three teams on action zones in the World Cup in 2018 using a Markov state transition matrix. [PDF]
Front Psychol, 2022 Liu T +5 more
europepmc +1 more source