Results 81 to 90 of about 115,259 (306)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Developments in the hydrogenation of challenging substrates utilising transition metal complexes
This thesis describes the developments of new protocols for the hydrogenation of challenging substrates. Three specific substrates were highlighted for study after an initial review of the literature; benzofurans, esters and bulky ketones.
Ian Carpenter, Carpenter, Ian
core
The ERC (Advanced Investigator Award-FUNCAT), Syngenta, and the EPSRC are gratefully thanked for support of this work. S.P.N. is a Royal Society Wolfson Research Merit Award holder.Gold(I) complexes of dibenzotropylidene-functionalized N-heterocyclic ...
Slawin, Alexandra MZ +17 more
core +1 more source
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Anticancer Metallocenes and Metal Complexes of Transition Elements from Groups 4 to 7
With the progression in the field of bioinorganic chemistry, the role of transition metal complexes as the most widely used therapeutics is becoming a more and more attractive research area.
Irena Kostova
doaj +1 more source
Synthesis and charaterisation of phosphorescent copper (I) complexes for light emitting devices [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Over the last decade, many significant developments have been made to improve the active materials in a new generation of organic light emitting devices ...
Andrés-Tomé, María Inmaculada
core
Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Hands-Portman, Ian +5 more
core +1 more source
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez +5 more
wiley +1 more source
The Journal of Transition Metal Complexes is a scholarly open access, peer-reviewed, and fully refereed journal. It presents original papers, reviews, and communications on all aspects of theoretical and experimental transition metal complex chemistry ...
Santini Carlo
core

