Results 101 to 110 of about 1,163,865 (262)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Transition model for coronavirus management. [PDF]
Can J Econ, 2022 Djogbenou A +4 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Disorder-to-order transition in one-dimensional nonreciprocal Cahn-Hilliard model
Physical Review ResearchWe present the phenomenology of the one-dimensional nonreciprocal Cahn-Hilliard model for varying nonreciprocity (α) and different boundary conditions. At small α, a perturbed uniform state evolves to a defect-laden configuration that lacks global polar ...
Navdeep Rana, Ramin Golestanian
doaj +1 more source
Performance of standardized cancer patient pathways in Sweden visualized using observational data and a state-transition model. [PDF]
Sci Rep, 2023 Borg S +5 more
europepmc +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Development and validation of an individual-based state-transition model for the prediction of frailty and frailty-related events. [PDF]
PLoS One, 2023 Pincombe A +3 more
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Evaluating the network security by the ReadWrite transition model
Tongxin xuebao, 2010 The ReadWrite transition model and correlative concepts were presented for the root directory with ReadWrite privilege setting; then the model transition function was formalized by the state transition arithmetic operator . Based on the transition model,
LU Zhi-yong1, 2, FENG Chao1, YU Hui2
doaj +2 more sources