Results 211 to 220 of about 1,438,980 (312)

Co-producing a transition model of care for eating disorders: lessons learned from a multi-perspective qualitative study with young people, carers and mental health professionals. [PDF]

J Eat Disord
Livanou M, Heneghan A, Hill G, McKenzie A, Marlais M, Marshall F, Smalley Z, Xanthopoulou E, Kornai N, Wilks J, McKay A, Teh J, Taylor I, Burton C, Baudinet J.   +14 more
europepmc   +1 more source

Functional network alterations differently associated with suicidal ideas and acts in depressed patients: an indirect support to the transition model. [PDF]

Transl Psychiatry, 2021
Wagner G, Li M, Sacchet MD, Richard-Devantoy S, Turecki G, Bär KJ, Gotlib IH, Walter M, Jollant F.   +8 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

A Multidimensional Array Representation of State-Transition Model Dynamics. [PDF]

Med Decis Making, 2020
Krijkamp EM, Alarid-Escudero F, Enns EA, Pechlivanoglou P, Hunink MGM, Yang A, Jalal HJ.   +6 more
europepmc   +1 more source

Development of the Fearless, Tearless Transition model of care for adolescents with an intellectual disability and/or autism spectrum disorder with mental health comorbidities. [PDF]

Dev Med Child Neurol, 2021
Culnane E, Loftus H, Efron D, Williams K, Di Iorio N, Shepherd R, Marraffa C, Lubitz L, Antolovich G, Prakash C.   +9 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Risk Function of Breast and Ovarian Cancers in the Avrami-Dobrzyński Cellular Phase-Transition Model. [PDF]

Int J Mol Sci
Zawadzka A, Brzozowska B, Matyjanka A, Mikula M, Reszczyńska J, Tartas A, Fornalski KW.   +6 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The Transition of the Care Model

Revista Brasileira de Geriatria e Gerontologia
João Bastos Freire Neto
doaj   +1 more source

Combination Treatment of Timosaponin BII and Pirfenidone Attenuated Pulmonary Fibrosis Through Anti-Inflammatory and Anti-Fibrotic Process in Rodent Pulmonary Fibrosis Model and Cellular Epithelial-Mesenchymal Transition Model. [PDF]

Molecules
Shen X, Zheng Y, Yang H, Liu L, Yu L, Zhang Y, Song X, He Y, Jin R, Jiao J, Gu Z, Zhai K, Nian S, Liu L.   +13 more
europepmc   +1 more source