Results 61 to 70 of about 490,730 (291)

Analysis and Simulation of a Two-Stage Blocked Tandem Queueing System

Journal of New Theory, 2021
In this paper, a new blocked tandem queueing model is given and analysed. The arrival process to this queueing model is Poisson with parameter λ.
Erdinç Yücesoy, Vedat Sağlam
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Latent transition analysis of instrumental activities of daily living in Chinese elderly: based on the 2014–2018 wave of the Chinese Longitudinal Healthy Longevity Survey

BMC Geriatrics
Background The instrumental activities of daily living (IADL) among the elderly have been found to be heterogeneous, with different trajectories. However, the transition of the IADL over time remains unclear.
Yaqi Wang, Xueying Xu, Jingwen Liu, Qingyun Lv, Hairong Chang, Yuan He, Yue Zhao, Xiaonan Zhang, Xiaoying Zang   +8 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Multiplatform Computing of Transition Probabilities in Os V

Atoms
Osmium is an element of the Periodic Table with an atomic number Z equal to 76. In Tokamaks with divertors made of tungsten (Z=74), it is produced in the neutron-induced transmutation of the latter.
Patrick Palmeri, Saturnin Enzonga Yoca, Exaucé Bokamba Motoumba, Alix Niels, Maxime Brasseur, Pascal Quinet   +5 more
doaj   +1 more source

FCCU transition-probability model

Mathematical and Computer Modelling, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Robbie J. Dixon, Maki Matsuka, Roger D. Braddock, Joshua Matthew Whitcombe, Igor E. Agranovski   +4 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Non Unitary Random Walks [PDF]

Discrete Mathematics & Theoretical Computer Science, 2009
Motivated by the recent refutation of information loss paradox in black hole by Hawking, we investigate the new concept of {\it non unitary random walks}.
Philippe Jacquet
doaj   +1 more source

ChoiceRank: Identifying Preferences from Node Traffic in Networks [PDF]

, 2017
Understanding how users navigate in a network is of high interest in many applications. We consider a setting where only aggregate node-level traffic is observed and tackle the task of learning edge transition probabilities.
Grossglauser, Matthias, Maystre, Lucas
core   +1 more source