Results 51 to 60 of about 292,642 (264)
Electron-acoustic phonon field induced tunnel scattering
Condensed Matter Physics, 2015 Theory of electron-acoustic single phonon scattering has been reconsidered. It is assumed that the non-degenerate semiconductor has a spherical parabolic band structure.
S.V. Melkonyan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A Regression-Based Procedure for Markov Transition Probability Estimation in Land Change Modeling
Land, 2020 Land change models commonly model the expected quantity of change as a Markov chain. Markov transition probabilities can be estimated by tabulating the relative frequency of change for all transitions between two dates.
J. Ronald Eastman, Jiena He
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Adaptive estimation of HMM transition probabilities [PDF]
Proceedings of 35th IEEE Conference on Decision and Control, 1996 This paper presents new schemes for recursive estimation of the state transition probabilities for hidden Markov models (HMMs) via recursive prediction error (RPE) methods. These new schemes are designed to be consistent and well conditioned, compared to the previous RPE schemes which are known to be ill-conditioned in low noise environments.
Jason J. Ford, John B. Moore
openaire +3 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Neural Correlate of Transition Violation and Deviance Detection in the Songbird Auditory Forebrain
Frontiers in Systems Neuroscience, 2018 Deviants are stimuli that violate one's prediction about the incoming stimuli. Studying deviance detection helps us understand how nervous system learns temporal patterns between stimuli and forms prediction about the future. Detecting deviant stimuli is
Mingwen Dong, David S. Vicario
doaj +1 more source
FCCU transition-probability model
Mathematical and Computer Modelling, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Robbie J. Dixon +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source