Results 71 to 80 of about 2,507,189 (293)

Transition Probabilities of Disablement for Malaysian Population in Need of Long-Term Care

open access: yesASM Science Journal, 2020
This research aims to estimate the transition probabilities of lives becoming disabled and the extent to which they are disabled using the approach of functional Markov model.
Syazreen Niza Shair
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluation of transition rates from nonequilibrium instantons

open access: yesPhysical Review Research
Equilibrium rate theories play a crucial role in understanding rare, reactive events. However, they are inapplicable to a range of irreversible processes in systems driven far from thermodynamic equilibrium like active and biological matter.
Eric R. Heller, David T. Limmer
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Open and Distance Learning and Information and Communication Technologies- Implications on Formal and Non formal Education.

open access: yesJournal of Learning for Development, 2015
The Population; female (% of total) in Kenya was last reported at 50.05 in 2011, according to a World Bank report published in 2012. Despite this higher percentage, women in Kenya are not well represented in education and training compared to their male ...
David Barasa Situma
doaj  

TRANSITION IN AGRICULTURE – REVIEW ON SUBSIDY AND CUSTOM RATES EFFECTS IN APPLE PRODUCTION IN BOSNIA AND HERZEGOVINA [PDF]

open access: yesJournal of Central European Agriculture, 2006
Speaking about transition in agriculture, we think on agriculture in transition countries, that is Central and Eastern European Countries. Such development is observed from the perspective of the European Union, discussing about possibilities as well as ...
F ĆEJVANOVIĆ, R FRANIĆ, Č ROZMAN
doaj  

Computing voter transitions: The elections for the Catalan Parliament, from 2010 to 2012

open access: yesJournal of Industrial Engineering and Management, 2015
Purpose: To estimate the transition rates corresponding to the 2010 and 2012 elections to the Catalan Parliament for the four constituencies in which Catalonia is divided for this purpose.
Albert Corominas   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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