Results 111 to 120 of about 1,119,090 (297)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The Regime Shift Associated with the 2004-2008 US Housing Market Bubble.

open access: yesPLoS ONE, 2016
The Subprime Bubble preceding the Subprime Crisis of 2008 was fueled by risky lending practices, manifesting in the form of a large abrupt increase in the proportion of subprime mortgages issued in the US.
James Tan, Siew Ann Cheong
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Kinetic and finite ion mass effects on the transition to relativistic self-induced transparency in laser-driven ion acceleration

open access: yesNew Journal of Physics, 2017
We study kinetic effects responsible for the transition to relativistic self-induced transparency in the interaction of a circularly-polarized laser-pulse with an overdense plasma and their relation to hole-boring (HB) and ion acceleration.
E Siminos   +3 more
doaj   +1 more source

Capillary focusing close to a topographic step: Shape and instability of confined liquid filaments

open access: yes, 2014
Step-emulsification is a microfluidic technique for droplet generation which relies on the abrupt decrease of confinement of a liquid filament surrounded by a continuous phase.
Afkhami, S.   +3 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Impact of the Applied Exchange Rate Regimes on the Internal Balance of Transition Countries

open access: yesECONOMICS, 2017
One of the key goals of the economic policy makers of every country is to achieve internal and external balance. An unavoidable segment of the analysis concerning the achievement of internal and external balance is certainly the influence of the exchange
Vujanić Vlado, Gligorić Dragan
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tuning the Mutual Synchronization of Electrically Coupled Spin‐Torque Oscillators by Selecting the Vortex Dynamic Regime

open access: yesAdvanced Electronic Materials
In this study, the synchronization ability of vortex‐based spin‐torque nano‐oscillators is investigated for three different dynamical regimes: the fundamental gyrotropic mode, the dynamic C‐state, and the transition regime characterized by stochastic ...
Miguel Romera   +11 more
doaj   +1 more source

The illusion of the shared electric automated mobility transition

open access: yesTransportation Research Interdisciplinary Perspectives
Shared electric automated vehicles (AVs) are advertised as the silver bullet for the sustainable transition of private internal combustion engine-based automobility by private and public entities.
Dimitris Milakis, Dennis Seibert
doaj   +1 more source

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