Results 91 to 100 of about 3,020,746 (299)
Experimental study of the brittle–ductile transition in hot cutting of SG iron specimens [PDF]
http://www.sciencedirect.com/science/article/pii/S0924013612002579The present paper investigates the brittle-ductile transition (BDT) of the primary shear zone during cutting of spheroidal graphite (SG) iron in the austenitization temperature range ...
EL MANSORI, Mohamed +2 more
core +1 more source
Analysis of Bridging Formulae in Transitional Regime
The most suitable method to compute aerodynamic forces of a spacecraft, at first stage of a design, relies on bridging formulae. There are two kinds of bridging formulae: global and local. The global formulae rely on knowledge of spacecraft aerodynamic force coefficients in continuum and in free molecular flow.
MORSA, LUIGI +3 more
openaire +3 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Inequality, Fiscal Capacity and the Political Regime: Lessons from the Post-Communist Transition [PDF]
Using panel data for twenty-seven post-communist economies between 1987-2003, we examine the nexus of relationships between inequality, fiscal capacity (defined as the ability to raise taxes efficiently) and the political regime. Investigating the impact
Christopher Gerry, Tomasz Mickiewicz
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The Emergence of a New ‘Socialist’ Market Labour Regime in China [PDF]
China’s transition to a market economy has been a process of basic institutional changes and institution building. The institutional change from a socialist labour regime (SLR) as one of the backbones upholding the traditional leninist system to a new ...
Günter Schucher, Jutta Hebel
core
Evolutionary regime transitions in structured populations
The evolutionary dynamics of a finite population where resident individuals are replaced by mutant ones depends on its spatial structure. Usually, the population adopts the form of an undirected graph where the place occupied by each individual is represented by a vertex and it is bidirectionally linked to the places that can be occupied by its ...
Fernando Alcalde Cuesta +2 more
openaire +7 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source

