Results 91 to 100 of about 1,119,090 (297)
Bifurcation patterns of market regime transition [PDF]
9 pages,4 ...
openaire +2 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Incorporation of Obstacle Hardening into Local Approach to Cleavage Fracture to Predict Temperature Effects in the Ductile to Brittle Transition Regime. [PDF]
Yankova MS, Jivkov AP, Patel R.
europepmc +1 more source
Quantum invariants of motion in a generic many-body system
Dynamical Lie-algebraic method for the construction of local quantum invariants of motion in non-integrable many-body systems is proposed and applied to a simple but generic toy model, namely an infinite kicked $t-V$ chain of spinless fermions ...
Kirchner S, Prosen T, Tomaz Prosen
core +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Superradiant Laser: First-Order Phase Transition and Non-stationary Regime
We solve the superradiant laser model in two limiting cases. First the stationary low-pumping regime is considered where a first-order phase transition in the semiclassical solution occurs. This discontinuity is smeared out in the quantum regime. Second,
Haake, Fritz +2 more
core +1 more source
Transition regimes for growing crack populations
Numerous observational papers on crack populations in the material and geological sciences suggest that cracks evolve in such a way as to organize in specific patterns. However, very little is known about how and why the self-organization comes about. We use a model of tensilelike cracks with friction in order to study the time and space evolution of ...
Spyropoulos, Chrysanthe +2 more
openaire +4 more sources
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Spontaneous transition to a fast 3D turbulent reconnection regime
We show how the conversion of magnetic field energy via magnetic reconnection can progress in a fully three-dimensional, fast, volume-filling regime.
Bemporad A. +13 more
core +1 more source

