Results 71 to 80 of about 3,020,746 (299)

Linking Radiative‐Advective Equilibrium Regime Transition to Arctic Amplification

open access: yesGeophysical Research Letters
Emission of anthropogenic greenhouse gases has resulted in greater Arctic warming compared to global warming, known as Arctic amplification (AA). From an energy‐balance perspective, the current Arctic climate is in radiative‐advective equilibrium (RAE ...
Yu‐Chiao Liang   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Regime transition, uncertainty and prospects for democratization: The politics for Russia's regions in a comparative perspective [PDF]

open access: yes
In analyzing regime transition as an open-ended process, the paradigmatic approach of the paper provides an alternative to teleological schemes of the transition to democracy.
Gel'man, Vladimir
core  

Poland’s Renewable Energy Transition (2010–2023): A Fuzzy Time Series and Multi-Criteria Assessment of Transition Quality in Electricity Production

open access: yesEnergies
This study evaluates the quality and dynamics of the renewable energy transition in Poland’s electricity sector during the years 2010–2023 through an integrated Fuzzy Time Series (FTS) and Fuzzy Multi-Criteria Evaluation (FMCE) methodology.
Bożena Gajdzik   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Maastricht & the Choice of Exchange Rate Regime in Transition Countries during the Run-Up to EMU. ENEPRI Working Paper No. 6, May 2001 [PDF]

open access: yes, 2000
This paper raises some specific issues concerning the choice of exchange rate regime in transition countries during the run-up to EU/EMU membership.
Szapáry, György., Szapary, Gy\uf6rgy
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

De facto and official exchange rate regimes in transition economies [PDF]

open access: yes
This paper provides an empirical investigation on the discrepancies between official exchange rate regimes and de facto exchange rate policies in transition economies. Since official and de facto regime choices are not independent of each other, we adopt
von Hagen, Jürgen, Zhou, Jizhong
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Estimation of Markov regime-switching regression models with endogenous switching [PDF]

open access: yes
Following Hamilton (1989), estimation of Markov regime-switching regressions nearly always relies on the assumption that the latent state variable controlling the regime change is exogenous.
Richard Startz   +2 more
core  

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