Results 81 to 90 of about 3,020,746 (299)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Currency Regime Choice: A Survey of Empirical Literature [PDF]

open access: yes
This paper reviews the empirical literature on the choice of exchange rate regime. Prominent issues include: (i) the choice based on fundamentals, shocks, financial structure, and political ideology; (ii) the “bipolar view” or “hollowing out hypothesis ...
Monzur Hossain
core  

A conceptual model for analyzing the stability condition and regime transition in bubble columns

open access: yes, 2010
The abrupt change on the curve of gas holdup vs. superficial gas velocity calculated from the dual-bubble-size (DBS) model was physically interpreted as a shift from the homogeneous and transition regimes to the heterogeneous regime for bubble columns in
Li, Jinghai   +4 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Pemodelan Saham Sektor Energi Menggunakan Non-Homogeneous Markov Switching Autoregressive (NHMS-AR) dengan Probabilitas Transisi Non-Homogeneous

open access: yesNumerical: Jurnal Matematika dan Pendidikan Matematika
The movement of energy sector stock returns is dynamic and influenced by external factors that cause changes in market conditions over time. These characteristics indicate the existence of regime shifts that cannot be optimally modeled using ...
Adam Fahmi Fandisyah   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Formulas for Friction Factor in Transitional Regimes [PDF]

open access: yesJournal of Hydraulic Engineering, 2008
This note concerns variations of the friction factor in the two transitional regimes, one between laminar and turbulent flows and the other between fully smooth and fully rough turbulent flows. An interpolation approach is developed to derive a single explicit formula for computing the friction factor in all flow regimes.
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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