Results 101 to 110 of about 1,119,090 (297)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The Semiclassical Regime of the Chaotic Quantum-Classical Transition
, 2005 An analysis of the semiclassical regime of the quantum-classical transition is given for open, bounded, one dimensional chaotic dynamical systems. Environmental fluctuations -- characteristic of all realistic dynamical systems -- suppress the development
Greenbaum, Benjamin D. +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Authoritarian Regimes in Transition
The Washington Quarterly, 1987 John C. Campbell, Hans Binnendijk
+5 more sources
Regime transition, uncertainty and prospects for democratization: The politics for Russia's regions in a comparative perspective [PDF]
In analyzing regime transition as an open-ended process, the paradigmatic approach of the paper provides an alternative to teleological schemes of the transition to democracy.
Gel'man, Vladimir
core
Anomalous fluctuation regimes at FFLO transition
Europhysics Letters (EPL), 2007 6 pages, 2 figures. Work supported by ANR Extreme Conditions Correlated Electrons (ANR-06-BLAN-0220)
Konschelle, Francois +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Density fluctuations and phase separation in a traffic flow model
, 1998 Within the Nagel-Schreckenberg traffic flow model we consider the transition from the free flow regime to the jammed regime. We introduce a method of analyzing the data which is based on the local density distribution.
Lubeck, S. +2 more
core +2 more sources
The vortex depinning transition in untwinned YBaCuO using complex impedance measurements
, 2003 We present surface impedance measurement of the vortex linear response in a large untwinned YBCO crystal. The depinning spectra obtained over a broad frequency range (100 Hz- 30 MHz) are those of a surface pinned vortex lattice with a free flux flow ...
A. Pautrat +12 more
core +2 more sources
Thinking about post-transitional demographic regimes [PDF]
Demographic Research, 2013 BACKGROUND For the last 70 years the concept of the demographic transition has provided a basis for understanding and predicting population trends in the developing world. However, a majority of the developing world's population will soon be post-transitional - what will happen then?
openaire +4 more sources