Results 71 to 80 of about 5,147,352 (245)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Canine urethral transitional cell carcinoma [PDF]
, 2003 The following case report describes the presentation and diagnostic evaluation of a 6-year-old spayed female mixed breed dog, with a 1.5-month history of dysuria, that was referred to the Small Animal Oncology Service at Cornell University's College of
Dampf, Melissa
core +4 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
, 2023 This article explores the nexus between ecoterritorial conflict resolution and transformative transitional justice, against the background of (neo)extractivism and the Peruvian case of half a century of oil violence. Our argument is twofold.
Kerremans, SarahRE220002105283928020037817230000-0002-8661-530X17d4f340-fc82-11eb-a75e-92367c4e9e59 +1 more
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Transitional Justice and Colonialism
, 2023 This chapter examines the reasons behind and the implications of the lack of, or poor, engagement of transitional justice with colonialism. Transitional justice has become the major framework in the international system for dealing with mass harm, and a ...
Yusuf, H. O.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The initial temperature field in an impulsively started thick plate,
, 2003 EUROTHERM SEMINAR 74, HEAT TRANSFER IN UNSTEADY AND TRANSITIONAL FLOWS, MARCH 23-26, 2003, EINDHOVEN, PAESI BASSI, PAG.105 ...
POZZI, AMILCARE +3 more
core +1 more source
Transitional Cell Carcinoma of the Ovary
Taiwanese Journal of Obstetrics & Gynecology, 2006 Objective: Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with ...
Chia-Hui Lin +2 more
doaj +1 more source