Results 101 to 110 of about 315,406 (303)

Single-cell analysis of p53 transitional dynamics unravels stimulus- and cell type-dependent signaling output motifs. [PDF]

BMC Biol, 2022
Xie J, Zhang L, Liu B, Liang X, Shi J.
europepmc   +1 more source

Equilibrium dynamics in two-sector models of endogenous growth. [PDF]

This paper presents an account of the dynamics of endogenous growth models with physical capital and human capital. We consider some important extensions of the basic framework of Lucas (1988) and Uzawa (1964), including physical capital in the human ...
Ladrón de Guevara, Antonio, Ortigueira, Salvador, Santos, Manuel S.   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Simulation of financial institutions activity in transitional economies [PDF]

The paper reviews the concepts of system dynamics and its applications to the simulation modeling of financial institutions daily activity. While widely applicable, the approach is of a particular interest in transitional and developing economies.
Rumyantsev, Mikhail I.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A 14‐Year Study of Serum Glial Fibrillary Acidic Protein and Total Tau in Premanifest Huntington's

Annals of Clinical and Translational Neurology
There is a pressing need for blood biomarkers that can identify Huntington's disease (HD) gene carriers' proximity to manifest disease. We previously examined serial serum neurofilament light (NfL) concentrations in 21 premanifest HD gene carriers and 14
Natalia E. Owen, Zanna J. Voysey, Jonathan A. Holbrook, Maura Malpetti, Clara Le Draoulec, Lennart R. B. Spindler, Anna O. G. Goodman, Alpar S. Lazar, Roger A. Barker   +8 more
doaj   +1 more source

Trauma social, memoria colectiva y paradojas de las políticas de Olvido en el Uruguay tras el terror de Estado (1973-1985): memoria generacional de la post-dictadura (1985-2015)

ILCEA, 2016
This work asks how the collective memory of socially traumatic experiences after state terrorism in Uruguay have endured to be transmitted across generations, in the context of transitional policies of Oblivion, extreme policies aimed at social silencing
Gabriela Fried Amilivia
doaj   +1 more source

Real Exchange Rate and Human Capital in the Empirics of Economic Growth [PDF]

This paper discusses the relative importance of transitional dynamics and steady state issues in growth. A new perspective is proposed about this debate, marked by different views. We argue that it is also important to consider the dynamics of economies,
Delfim Gomes Neto
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Molecular simulation of methane adsorption capacity in transitional shale – a case study of Longtan Formation shale in Southern Sichuan Basin, SW China

Open Geosciences
It is of great significance to clarify the shale gas occurrence mechanism under formation condition for the exploration and development of transitional shale gas reservoir.
Chen Weiming, Qi Lin, Lin Renkui, Tang Bangdi, Dai Dongyu, Zheng Jie   +5 more
doaj   +1 more source