Results 121 to 130 of about 315,406 (303)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Physical aspects of computing the flow of a viscous fluid [PDF]

One of the main themes in fluid dynamics at present and in the future is going to be computational fluid dynamics with the primary focus on the determination of drag, flow separation, vortex flows, and unsteady flows.
Mehta, U. B.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Money Demand and the Potential of Seigniorage in China. [PDF]

Since 1978 China has been experiencing a strong monetary growth. However annual inflation has not exceeded 20%. One of the outcomes has been a high level of seigniorage.
Geneviève BOYREAU-DEBRAY
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Dynamic mesophase transition induces anomalous suppressed and anisotropic phonon thermal transport

npj Computational Materials
The physical/chemical properties undergo significant transformations in the different states arising from phase transition. However, due to the lack of a dynamic perspective, transitional mesophases are largely underexamined, constrained by the high ...
Linfeng Yu, Kexin Dong, Qi Yang, Yi Zhang, Zheyong Fan, Xiong Zheng, Huimin Wang, Zhenzhen Qin, Guangzhao Qin   +8 more
doaj   +1 more source

River-to-Lake Transitional Areas Contribute Disproportionately to In-Lake Nutrient Loading

Ocean-Land-Atmosphere Research
River-to-lake transitional areas are biogeochemically active sections of the aquatic continuum that are often understudied compared to their adjoining environments.
Nolan J. T. Pearce, James H. Larson, Rebecca M. Kreiling, Mary Anne Evans, Sean W. Bailey, Kenna J. Gierke, Lynn A. Bartsch, Marguerite A. Xenopoulos, Paul C. Frost   +8 more
doaj   +1 more source

Emergence of stochastic dynamics in plane Couette flow [PDF]

, 2016
Spatially localized states play an important role in transition to turbulence in shear flows (Kawahara, Uhlmann & van Veen, Annu. Rev. Fluid Mech. 44, 203 (2012)).
Beaume, C, Gvalani, R
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Asset Accumulation, Fertility Choice and Nondegenerate Dynamics in a Small Open Economy [PDF]

This paper shows that the assumption of elastic fertility choices represents an unconsidered way of introducing nondegenerate dynamics within an immortal small open economy, facing perfect capital mobility and no adjustment costs associated with capital ...
Alberto Petrucci
core