Results 111 to 120 of about 315,406 (303)

A Model of Quality Ladders with Horizontal Entry [PDF]

We develop a multi-sector model of R&D-driven endogenous growth that merges the expanding-variety with the quality-ladders mechanism. The mechanism of expanding variety provides the flow of new firms (new product lines), whilst the mechanism of quality ...
Paulo Brito, Pedro Rui Mazeda Gil, Óscar Afonso   +2 more
core  

Stochastic Dynamics for Video Infilling

, 2019
In this paper, we introduce a stochastic dynamics video infilling (SDVI) framework to generate frames between long intervals in a video. Our task differs from video interpolation which aims to produce transitional frames for a short interval between ...
Belhumeur, Peter N., Neumann, Ulrich, Wang, Weiyue, Xu, Qiangeng, Zhang, Hanwang   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

General Purpose Technologies and their Implications for International Trade

International Journal of Management and Economics, 2015
This paper develops a simple model of trade and “quality-ladders” growth without scale effects to study the implications of general purpose technologies (GPTs) for international trade.
Petsas Iordanis
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Validating clustering of molecular dynamics simulations using polymer models

BMC Bioinformatics, 2011
Background Molecular dynamics (MD) simulation is a powerful technique for sampling the meta-stable and transitional conformations of proteins and other biomolecules.
Phillips Joshua L, Colvin Michael E, Newsam Shawn   +2 more
doaj   +1 more source

Investigation of Transitional Shock-Wave/Boundary Layer Interactions Using Direct Numerical Simulations [PDF]

Interaction of a transitional boundary layer with a normal-shock is investigated using unstructured tetrahedral meshes under the numerical framework of the space-time conservation element, solution element (CESE) method.
Chang, Chau-Lyan, Venkatachari, Balaji Shankar   +1 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Transitional Dynamics of Fiscal Policy in Small Open Economies. [PDF]

The paper studies the dynamic macroeconomic effects of fiscal shocks of various duration (permanent and temporary) under different financing methods (lump-sum tax and government debt).
Heijdra, B.J., Ligthart, J.E.
core   +4 more sources

Divergence in Economic Performance: Transitional Dynamics with Multiple Equilibria [PDF]

Special pairs of the utility functions and the production functions are used in this paper to uncover the transitional dynamics in a Lucas model of growth. The main findings are as follows: A continuum of equilibria exists if the external effect of human
Danyang Xie
core